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Drosophila (fly)

Content tagged with Drosophila (fly)

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Important new considerations for TRiP stock users

News
A handful of recent papers and preprints have highlighted some important considerations for using TRiP shRNA and sgRNA stocks. First, the Weake lab at Purdue University discovered that TRiP stocks contain a previously uncharacterized loss-of-function...

Read the DRSC/TRiP Report to the Fly Board 2022

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Below we share with the community at large the report we provided to the Fly Board in advance of the 2022 Fly Meeting. As always, your feedback on our technologies and services is welcome. We are here to help. DRSC/TRiP Functional Genomics Resources at...

DRSC/TRiP and DRSC-BTRR Office Hours

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New this fall: Online office hours! Do you have questions about modifying Drosophila cell lines with CRISPR or performing large-scale cell screens? Questions about in vivo RNAi with TRiP fly stocks or CRISPR knockout or activation with our sgRNA fly...

New publications from the DRSC bioinformatics team

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The DRSC bioinformatics team, led by Dr. Claire Yanhui Hu, has recently published two new papers. One reports development of BioLitMine, an advanced literature mining resource. The other provides an overview of our online resources, which can be grouped...

Transgenic Fly Stocks for Double Knockout of Paralog Pairs

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Paralogs can be defined as related genes within a genome that are thought to arise from gene duplication events. Because paralogous proteins share amino acid identity, they can have redundant functions. But the picture is not necessarily so...

Bibliographic References tagged with Drosophila (fly)

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Alfeu Zanotto-Filho, Ravi Dashnamoorthy, Eva Loranc, Luis Souza, José Moreira, Uthra Suresh, Yidong Chen, and Alexander Bishop. 2016. “Combined Gene Expression and RNAi Screening to Identify Alkylation Damage Survival Pathways from Fly to Human.”. PLoS One, 11, 4, Pp. e0153970. doi:10.1371/journal.pone.0153970
Alfeu Zanotto-Filho, Ravi Dashnamoorthy, Eva Loranc, Luis Souza, José Moreira, Uthra Suresh, Yidong Chen, and Alexander Bishop. 2016. “Combined Gene Expression and RNAi Screening to Identify Alkylation Damage Survival Pathways from Fly to Human.”. PLoS One, 11, 4, Pp. e0153970. doi:10.1371/journal.pone.0153970
Shu Kondo and Norbert Perrimon. 2011. “A Genome-Wide RNAi Screen Identifies Core Components of the G₂-M DNA Damage Checkpoint.”. Sci Signal, 4, 154, Pp. rs1. doi:10.1126/scisignal.2001350
Shu Kondo and Norbert Perrimon. 2011. “A Genome-Wide RNAi Screen Identifies Core Components of the G₂-M DNA Damage Checkpoint.”. Sci Signal, 4, 154, Pp. rs1. doi:10.1126/scisignal.2001350
Vig, Peinelt, Beck, Koomoa, Rabah, Koblan-Huberson, Kraft, Turner, Fleig, Penner, and Kinet. 2006. “CRACM1 Is a Plasma Membrane Protein Essential for Store-Operated Ca2+ Entry.”. Science, 312, 5777, Pp. 1220-3. doi:10.1126/science.1127883
Vig, Peinelt, Beck, Koomoa, Rabah, Koblan-Huberson, Kraft, Turner, Fleig, Penner, and Kinet. 2006. “CRACM1 Is a Plasma Membrane Protein Essential for Store-Operated Ca2+ Entry.”. Science, 312, 5777, Pp. 1220-3. doi:10.1126/science.1127883
Matthew Booker, Anastasia Samsonova, Young Kwon, Ian Flockhart, Stephanie Mohr, and Norbert Perrimon. 2011. “False Negative Rates in Drosophila Cell-Based RNAi Screens: A Case Study.”. BMC Genomics, 12, Pp. 50. doi:10.1186/1471-2164-12-50
Matthew Booker, Anastasia Samsonova, Young Kwon, Ian Flockhart, Stephanie Mohr, and Norbert Perrimon. 2011. “False Negative Rates in Drosophila Cell-Based RNAi Screens: A Case Study.”. BMC Genomics, 12, Pp. 50. doi:10.1186/1471-2164-12-50
Shenyuan Zhang, Andriy Yeromin, Xiang Zhang, Ying Yu, Olga Safrina, Aubin Penna, Jack Roos, Kenneth Stauderman, and Michael Cahalan. 2006. “Genome-Wide RNAi Screen of Ca(2+) Influx Identifies Genes That Regulate Ca(2+) Release-Activated Ca(2+) Channel Activity.”. Proc Natl Acad Sci U S A, 103, 24, Pp. 9357-62. doi:10.1073/pnas.0603161103
Shenyuan Zhang, Andriy Yeromin, Xiang Zhang, Ying Yu, Olga Safrina, Aubin Penna, Jack Roos, Kenneth Stauderman, and Michael Cahalan. 2006. “Genome-Wide RNAi Screen of Ca(2+) Influx Identifies Genes That Regulate Ca(2+) Release-Activated Ca(2+) Channel Activity.”. Proc Natl Acad Sci U S A, 103, 24, Pp. 9357-62. doi:10.1073/pnas.0603161103