Drosophila (fly)
Content tagged with Drosophila (fly)
Not finding what you're looking for? Try using Advanced Search.
Not finding what you're looking for? Try using Advanced Search.
News
As a facility that supports large-scale screens in Drosophila and other insect cell lines, we get excited about reports of new Drosophila cell lines and related info. We'd like to highlight two recent papers. One report, a collaboration between Amanda...
Light up your flies! Reagent and protocol information for application of our NanoTag system for epitope tagging in Drosophila
News
One of the areas of interest for our technology development group is nanobodies. These small, single-chain antibodies are particularly attractive for Drosophila research as in addition to being used for standard immune-technologies such as immunoblots and...
Important new considerations for TRiP stock users
News
A handful of recent papers and preprints have highlighted some important considerations for using TRiP shRNA and sgRNA stocks. First, the Weake lab at Purdue University discovered that TRiP stocks contain a previously uncharacterized loss-of-function...
So you want to do a CRISPR pooled screen in insect cells? You can! Here's how
News
At the DRSC-BTRR, we've been doing a lot of pooled-format CRISPR knockout screens in Drosophila cells. We're finding the results to be robust and reproducible. And best of all, the results have been informative, providing insights into diverse areas of...
Read the DRSC/TRiP Report to the Fly Board 2022
News
Below we share with the community at large the report we provided to the Fly Board in advance of the 2022 Fly Meeting. As always, your feedback on our technologies and services is welcome. We are here to help. DRSC/TRiP Functional Genomics Resources at...
DRSC/TRiP and DRSC-BTRR Office Hours
News
New this fall: Online office hours! Do you have questions about modifying Drosophila cell lines with CRISPR or performing large-scale cell screens? Questions about in vivo RNAi with TRiP fly stocks or CRISPR knockout or activation with our sgRNA fly...
New from the DRSC and Perrimon lab: DRscDB resource for mining of single-cell data sets
News
We are excited to launch our DRscDB online resource for mining of single-cell RNAseq data sets from Drosophila and other species. You can read more about the resource in our BioRxiv preprint.
New publications from the DRSC bioinformatics team
News
The DRSC bioinformatics team, led by Dr. Claire Yanhui Hu, has recently published two new papers. One reports development of BioLitMine, an advanced literature mining resource. The other provides an overview of our online resources, which can be grouped...
DRSC/TRiP presentations from June 2020 Boston Area Drosophila Meeting
News
Did you miss the presentations from Claire Hu and Jonathan Zirin at the June 2020 Boston Area Drosophila Meeting? No problem! The slides can be accessed from this post. Click the title above to view the whole post, then scroll down to access the PDFs...
Transgenic Fly Stocks for Double Knockout of Paralog Pairs
News
Paralogs can be defined as related genes within a genome that are thought to arise from gene duplication events. Because paralogous proteins share amino acid identity, they can have redundant functions. But the picture is not necessarily so...
Bibliographic References tagged with Drosophila (fly)
Not finding what you're looking for? Try using Advanced Search.
Not finding what you're looking for? Try using Advanced Search.
Alfeu Zanotto-Filho, Ravi Dashnamoorthy, Eva Loranc, Luis Souza, José Moreira, Uthra Suresh, Yidong Chen, and Alexander Bishop. 2016. “Combined Gene Expression and RNAi Screening to Identify Alkylation Damage Survival Pathways from Fly to Human.”. PLoS One, 11, 4, Pp. e0153970. doi:10.1371/journal.pone.0153970
Alfeu Zanotto-Filho, Ravi Dashnamoorthy, Eva Loranc, Luis Souza, José Moreira, Uthra Suresh, Yidong Chen, and Alexander Bishop. 2016. “Combined Gene Expression and RNAi Screening to Identify Alkylation Damage Survival Pathways from Fly to Human.”. PLoS One, 11, 4, Pp. e0153970. doi:10.1371/journal.pone.0153970
Shu Kondo and Norbert Perrimon. 2011. “A Genome-Wide RNAi Screen Identifies Core Components of the G₂-M DNA Damage Checkpoint.”. Sci Signal, 4, 154, Pp. rs1. doi:10.1126/scisignal.2001350
Shu Kondo and Norbert Perrimon. 2011. “A Genome-Wide RNAi Screen Identifies Core Components of the G₂-M DNA Damage Checkpoint.”. Sci Signal, 4, 154, Pp. rs1. doi:10.1126/scisignal.2001350
Vig, Peinelt, Beck, Koomoa, Rabah, Koblan-Huberson, Kraft, Turner, Fleig, Penner, and Kinet. 2006. “CRACM1 Is a Plasma Membrane Protein Essential for Store-Operated Ca2+ Entry.”. Science, 312, 5777, Pp. 1220-3. doi:10.1126/science.1127883
Vig, Peinelt, Beck, Koomoa, Rabah, Koblan-Huberson, Kraft, Turner, Fleig, Penner, and Kinet. 2006. “CRACM1 Is a Plasma Membrane Protein Essential for Store-Operated Ca2+ Entry.”. Science, 312, 5777, Pp. 1220-3. doi:10.1126/science.1127883
Matthew Booker, Anastasia Samsonova, Young Kwon, Ian Flockhart, Stephanie Mohr, and Norbert Perrimon. 2011. “False Negative Rates in Drosophila Cell-Based RNAi Screens: A Case Study.”. BMC Genomics, 12, Pp. 50. doi:10.1186/1471-2164-12-50
Matthew Booker, Anastasia Samsonova, Young Kwon, Ian Flockhart, Stephanie Mohr, and Norbert Perrimon. 2011. “False Negative Rates in Drosophila Cell-Based RNAi Screens: A Case Study.”. BMC Genomics, 12, Pp. 50. doi:10.1186/1471-2164-12-50
Shenyuan Zhang, Andriy Yeromin, Xiang Zhang, Ying Yu, Olga Safrina, Aubin Penna, Jack Roos, Kenneth Stauderman, and Michael Cahalan. 2006. “Genome-Wide RNAi Screen of Ca(2+) Influx Identifies Genes That Regulate Ca(2+) Release-Activated Ca(2+) Channel Activity.”. Proc Natl Acad Sci U S A, 103, 24, Pp. 9357-62. doi:10.1073/pnas.0603161103
Shenyuan Zhang, Andriy Yeromin, Xiang Zhang, Ying Yu, Olga Safrina, Aubin Penna, Jack Roos, Kenneth Stauderman, and Michael Cahalan. 2006. “Genome-Wide RNAi Screen of Ca(2+) Influx Identifies Genes That Regulate Ca(2+) Release-Activated Ca(2+) Channel Activity.”. Proc Natl Acad Sci U S A, 103, 24, Pp. 9357-62. doi:10.1073/pnas.0603161103