Mouse
Content tagged with Mouse
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News
We are excited to launch our DRscDB online resource for mining of single-cell RNAseq data sets from Drosophila and other species. You can read more about the resource in our BioRxiv preprint.
New publications from the DRSC bioinformatics team
News
The DRSC bioinformatics team, led by Dr. Claire Yanhui Hu, has recently published two new papers. One reports development of BioLitMine, an advanced literature mining resource. The other provides an overview of our online resources, which can be grouped...
Navigating our online tools -- orthologs, literature mining, qPCR primers, and so much more!
News
We have been taking a critical look at how we organize our online tools on the Online Tools Overview page. And more generally, we have been thinking about new ways to spread the word about the many resources in our suite of online tools. One way that we...
DRSC Bioinformatics launches iProteinDB and BioLitMine
News
We have two new online tools available: iProteinDB and BioLitMine. Both continue our series of resources aimed at integrating existing information in new ways to facilitate data mining and development of new hypotheses. In addition, iProteinDB includes a...
Variable Dose Analysis: a new DRSC-supported cell screen approach that leverages existing reagents to perform robust screens
News
We are excited to report the publication of a paper from Benjamin Housden and colleagues describing development and use of the Variable Dose Analysis (VDA) approach. Ben developed a way to use existing TRiP shRNA plasmids originally developed for fly...
Tutorial on DIOPT ortholog search tool scores, ranks and 'best' matches
News
In response to a request placed using our bug report form, we have put together a YouTube video demonstration that explains the scores, ranks, and 'best' matches that appear as part of the results tables at the DRSC Integrative Ortholog Precition Tool or...
New automated imaging at the DRSC
News
The DRSC/TRiP-FGR is pleased to announce that we recently updated our high-throughput, high-content imaging system. Through funds from NIH, HHMI, and the Harvard Medical School Tools & Technology program, we were able to get a GE IN Cell 6000 automated...
DIOPT 6.0 released -- with eggNOG and paralog searches added
News
DIOPT 6.0 went live this week. Newly added features include results from eggNOG, bringing the total number of alrogithms incorporated in our integrated search tool to 14. In addition, you can now search for paralogs. To do this, choose the same species...
Now Available: Our 2017 NAR database issue update
News
Read about the DRSC/TRiP Functional Genomics Resources online tools and more in our 2017 Nucleic Acids Research database issue update publication. Tables 1 & 2 in particular are meant to give you a quick look at what online tools we offer and how they fit...
"One vs. All" a new feature in our ortholog search tool
News
Our DIOPT ortholog search tool has been updated to include the option to search for orthologs of a gene in all other species included. So you can search with, for example, a fly gene, and see orthologs in human, mouse, rat, frog, worm, and yeast. Click on...
Bibliographic References tagged with Mouse
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Theresa Moser, Russell Jones, Craig Thompson, Carolyn Coyne, and Sara Cherry. 2010. “A Kinome RNAi Screen Identified AMPK As Promoting Poxvirus Entry through the Control of Actin Dynamics.”. PLoS Pathog, 6, 6, Pp. e1000954. doi:10.1371/journal.ppat.1000954
Theresa Moser, Russell Jones, Craig Thompson, Carolyn Coyne, and Sara Cherry. 2010. “A Kinome RNAi Screen Identified AMPK As Promoting Poxvirus Entry through the Control of Actin Dynamics.”. PLoS Pathog, 6, 6, Pp. e1000954. doi:10.1371/journal.ppat.1000954
Yanhui Hu, Ian Flockhart, Arunachalam Vinayagam, Clemens Bergwitz, Bonnie Berger, Norbert Perrimon, and Stephanie Mohr. 2011. “An Integrative Approach to Ortholog Prediction for Disease-Focused and Other Functional Studies.”. BMC Bioinformatics, 12, Pp. 357. doi:10.1186/1471-2105-12-357
Yanhui Hu, Ian Flockhart, Arunachalam Vinayagam, Clemens Bergwitz, Bonnie Berger, Norbert Perrimon, and Stephanie Mohr. 2011. “An Integrative Approach to Ortholog Prediction for Disease-Focused and Other Functional Studies.”. BMC Bioinformatics, 12, Pp. 357. doi:10.1186/1471-2105-12-357
Stephanie Mohr and Norbert Perrimon. 2012. “RNAi Screening: New Approaches, Understandings, and Organisms.”. Wiley Interdiscip Rev RNA, 3, 2, Pp. 145-58. doi:10.1002/wrna.110
Stephanie Mohr and Norbert Perrimon. 2012. “RNAi Screening: New Approaches, Understandings, and Organisms.”. Wiley Interdiscip Rev RNA, 3, 2, Pp. 145-58. doi:10.1002/wrna.110
Joshua Stender, Gabriel Pascual, Wen Liu, Minna Kaikkonen, Kevin Do, Nathanael Spann, Michael Boutros, Norbert Perrimon, Michael Rosenfeld, and Christopher Glass. 2012. “Control of Proinflammatory Gene Programs by Regulated Trimethylation and Demethylation of Histone H4K20.”. Mol Cell, 48, 1, Pp. 28-38. doi:10.1016/j.molcel.2012.07.020
Joshua Stender, Gabriel Pascual, Wen Liu, Minna Kaikkonen, Kevin Do, Nathanael Spann, Michael Boutros, Norbert Perrimon, Michael Rosenfeld, and Christopher Glass. 2012. “Control of Proinflammatory Gene Programs by Regulated Trimethylation and Demethylation of Histone H4K20.”. Mol Cell, 48, 1, Pp. 28-38. doi:10.1016/j.molcel.2012.07.020
Stephanie Stotz and David Clapham. 2012. “Anion-Sensitive Fluorophore Identifies the Drosophila Swell-Activated Chloride Channel in a Genome-Wide RNA Interference Screen.”. PLoS One, 7, 10, Pp. e46865. doi:10.1371/journal.pone.0046865
Stephanie Stotz and David Clapham. 2012. “Anion-Sensitive Fluorophore Identifies the Drosophila Swell-Activated Chloride Channel in a Genome-Wide RNA Interference Screen.”. PLoS One, 7, 10, Pp. e46865. doi:10.1371/journal.pone.0046865
Katharina Thiel, Christoph Heier, Verena Haberl, Peter Thul, Monika Oberer, Achim Lass, Herbert Jäckle, and Mathias Beller. 2013. “The Evolutionarily Conserved Protein CG9186 Is Associated With Lipid Droplets, Required for Their Positioning and for Fat Storage.”. J Cell Sci, 126, Pt 10, Pp. 2198-212. doi:10.1242/jcs.120493
Katharina Thiel, Christoph Heier, Verena Haberl, Peter Thul, Monika Oberer, Achim Lass, Herbert Jäckle, and Mathias Beller. 2013. “The Evolutionarily Conserved Protein CG9186 Is Associated With Lipid Droplets, Required for Their Positioning and for Fat Storage.”. J Cell Sci, 126, Pt 10, Pp. 2198-212. doi:10.1242/jcs.120493
Zheng Yin, Amine Sadok, Heba Sailem, Afshan McCarthy, Xiaofeng Xia, Fuhai Li, Mar Arias Garcia, Louise Evans, Alexis Barr, Norbert Perrimon, Christopher Marshall, Stephen Wong, and Chris Bakal. 2013. “A Screen for Morphological Complexity Identifies Regulators of Switch-Like Transitions Between Discrete Cell Shapes.”. Nat Cell Biol, 15, 7, Pp. 860-71. doi:10.1038/ncb2764
Zheng Yin, Amine Sadok, Heba Sailem, Afshan McCarthy, Xiaofeng Xia, Fuhai Li, Mar Arias Garcia, Louise Evans, Alexis Barr, Norbert Perrimon, Christopher Marshall, Stephen Wong, and Chris Bakal. 2013. “A Screen for Morphological Complexity Identifies Regulators of Switch-Like Transitions Between Discrete Cell Shapes.”. Nat Cell Biol, 15, 7, Pp. 860-71. doi:10.1038/ncb2764
Bahar Yilmazel, Yanhui Hu, Frederic Sigoillot, Jennifer Smith, Caroline Shamu, Norbert Perrimon, and Stephanie Mohr. 2014. “Online GESS: Prediction of MiRNA-Like Off-Target Effects in Large-Scale RNAi Screen Data by Seed Region Analysis.”. BMC Bioinformatics, 15, Pp. 192. doi:10.1186/1471-2105-15-192
Bahar Yilmazel, Yanhui Hu, Frederic Sigoillot, Jennifer Smith, Caroline Shamu, Norbert Perrimon, and Stephanie Mohr. 2014. “Online GESS: Prediction of MiRNA-Like Off-Target Effects in Large-Scale RNAi Screen Data by Seed Region Analysis.”. BMC Bioinformatics, 15, Pp. 192. doi:10.1186/1471-2105-15-192
Stephanie Mohr, Jennifer Smith, Caroline Shamu, Ralph Neumüller, and Norbert Perrimon. 2014. “RNAi Screening Comes of Age: Improved Techniques and Complementary Approaches.”. Nat Rev Mol Cell Biol, 15, 9, Pp. 591-600. doi:10.1038/nrm3860
Stephanie Mohr, Jennifer Smith, Caroline Shamu, Ralph Neumüller, and Norbert Perrimon. 2014. “RNAi Screening Comes of Age: Improved Techniques and Complementary Approaches.”. Nat Rev Mol Cell Biol, 15, 9, Pp. 591-600. doi:10.1038/nrm3860