The DRSC is collaborating with the Berkeley Drosophila Genome Project and the DFCI Center for Cancer Systems Biology on a large-scale Drosophila binary protein interaction project, the FlyBi project. We have deposited Drosophila ORFs in Gateway vectors at several repositories and recently began releasing unpublished preliminary data from the first of several rounds of yeast two-hybrid (Y2H) screening of Read more about Plasmid clones and data available from the FlyBi project

The TRiP is excited to announce our new TRiP-CRISPR transgenic fly libraries for gene knockout and overexpression. Visit the sgRNA tracking site to download and search existing TRiP-CRISPR fly stocks by gene or stock ID to obtain information on sgRNA sequence, function, vector, injection site, and availablility.

The database also has a nominations page that serves as the online access point for the public to nominate genes for eith Read more about The TRiP is now taking nominations for CRISPR stocks

Those of us lucky enough to be at the Annual Drosophila Research Conference this morning saw a great talk by Francois Payre about regulation of Shavenbaby by small ORFs. A genome-wide cell-based screen done at the DRSC by Emilie Benrabah identified the mechanism of regulation. As this exemplifies, cell screens can help identify key pathways and factors that can then be followed up with in vivo studies.