A handful of recent papers and preprints have highlighted some important considerations for using TRiP shRNA and sgRNA stocks.

First, the Weake lab at Purdue University discovered that TRiP stocks contain a previously...

At the DRSC-BTRR, we've been doing a lot of pooled-format CRISPR knockout screens in Drosophila cells. We're finding the results to be robust and reproducible. And best of all, the results have been informative, providing insights into diverse areas of biology.

Thinking about how to do CRISPR knockout screens in cells is a little different from thinking about how to do a genetic or RNAi screen in vivo or doing an arrayed-format RNAi screen....

Below we share with the community at large the report we provided to the Fly Board in advance of the 2022 Fly Meeting. As always, your feedback on our technologies and services is welcome. We are here to help.

DRSC/TRiP Functional Genomics Resources at Harvard Medical School

...