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2020 Apr 22

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Recent News

Photo of 384-well assay plates

Drosophila cell screen with DRSC reagent library contributes to identification of new therapeutic target for renal cancer

October 7, 2019

We here at the DRSC/TRiP are thrilled to see this study from Hilary Nicholson et al. published in Science Signaling.

The study provides a great example of how screens in Drosophila cultured cells can be used as part of a cross-species platform aimed at discovery of new targets for disease treatment. The work represents a collaboration between the laboratory of 2019 Nobel Prize winner W. Kaelin and DRSC PI N. Perrimon.

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Figure 1 from the Escobedo et al. micropublication

Micropublication relevant to TRiP fly stocks

April 9, 2019

Users of TRiP RNAi and sgRNA fly stocks take note: the Weake lab at Purdue University brought to our attention that some TRiP fly stocks carry a mutant allele of seveneless. Jonathan Zirin worked with Spencer Escobedo and Vikki Weake, as well as with folks at the Bloomington Drosophila Stock Center, to quickly identify the source, sequence the mutant allele, and pubilsh a micropublication so we can get the details to the community. Bottom line, as stated in the micropublication, "The presence of the sev[21]  mutation will not generally affect the use of these stocks, as the X...

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Screenshot of online tools

Navigating our online tools -- orthologs, literature mining, qPCR primers, and so much more!

February 14, 2019

We have been taking a critical look at how we organize our online tools on the Online Tools Overview page. And more generally, we have been thinking about new ways to spread the word about the many resources in our suite of online tools. One way that we at the DRSC like to think about these tools is how they fit into the start-to-finish order of events in a screen or other experimental project. Various tools help define lists of genes to be studied, help identify reagents for the study,...

Read more about Navigating our online tools -- orthologs, literature mining, qPCR primers, and so much more!
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