DIOPT-Diseases and Traits takes our DIOPT approach to ortholog mapping a step further. At DIOPT-DIST, model organism genes are mapped to putative orthologs in the human genome, and human genes are associated with disease-gene information. You can start with a gene or list of genes from a model species, or start with a disease term, then view model organism and human orthologs as well as disease information.






To request a tutorial video, please make the suggestion on our bug report form. Please also visit the DIOPT or DIOPT-DIST documentation pages, or read our paper (see below), for help with the tool.


Please see the DIOPT-DIST Documentation page.

Additional Resources

You might also be interested in our DIOPT ortholog search tool, the NIH Online Mendelian Inheritance in Man (OMIM) online database, the NIH Genetics Home Reference database, or the NIH catalog of results from genome-wide association studies (GWAS)

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