Human

Content tagged with Human

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New publications from the DRSC bioinformatics team

News
The DRSC bioinformatics team, led by Dr. Claire Yanhui Hu, has recently published two new papers. One reports development of BioLitMine, an advanced literature mining resource. The other provides an overview of our online resources, which can be grouped...

DRSC-Biomedical Technology Research Resource

News
We are pleased to announce that we have been funded by NIH NIGMS to form the Drosophila Research & Screening Center-Biomedical Technology Research Resource (DRSC-BTRR). The P41-funded DRSC-BTRR (N. Perrimon, PI; S. Mohr, Co-I) builds upon and extends past...

DRSC Bioinformatics launches iProteinDB and BioLitMine

News
We have two new online tools available: iProteinDB and BioLitMine. Both continue our series of resources aimed at integrating existing information in new ways to facilitate data mining and development of new hypotheses. In addition, iProteinDB includes a...

New automated imaging at the DRSC

News
The DRSC/TRiP-FGR is pleased to announce that we recently updated our high-throughput, high-content imaging system. Through funds from NIH, HHMI, and the Harvard Medical School Tools & Technology program, we were able to get a GE IN Cell 6000 automated...

DIOPT 6.0 released -- with eggNOG and paralog searches added

News
DIOPT 6.0 went live this week. Newly added features include results from eggNOG, bringing the total number of alrogithms incorporated in our integrated search tool to 14. In addition, you can now search for paralogs. To do this, choose the same species...

Bibliographic References tagged with Human

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Yanhui Hu, Aram Comjean, Jonathan Rodiger, Weihang Chen, Ah-Ram Kim, Mujeeb Qadiri, Chenxi Gao, Jonathan Zirin, Stephanie E Mohr, and Norbert Perrimon. 2024. “FlyRNAi.Org 2025 Update-Expanded Resources for New Technologies and Species.”. Nucleic Acids Research. doi:10.1093/nar/gkae917
Yanhui Hu, Aram Comjean, Jonathan Rodiger, Weihang Chen, Ah-Ram Kim, Mujeeb Qadiri, Chenxi Gao, Jonathan Zirin, Stephanie E Mohr, and Norbert Perrimon. 2024. “FlyRNAi.Org 2025 Update-Expanded Resources for New Technologies and Species.”. Nucleic Acids Research. doi:10.1093/nar/gkae917
Hans M. Dalton, Raghuvir Viswanatha, Ricky Brathwaite Jr., Jae Sophia Zuno, Stephanie Mohr, Norbert Perrimon, and Clement Y. Chow. 2021. “A Genome-Wide CRISPR Screen Identifies the Glycosylation Enzyme DPM1 As a Modifier of DPAGT1 Deficiency and ER Stress”. BioRxiv
Hans M. Dalton, Raghuvir Viswanatha, Ricky Brathwaite Jr., Jae Sophia Zuno, Stephanie Mohr, Norbert Perrimon, and Clement Y. Chow. 2021. “A Genome-Wide CRISPR Screen Identifies the Glycosylation Enzyme DPM1 As a Modifier of DPAGT1 Deficiency and ER Stress”. BioRxiv
Yanhui Hu, Sudhir Gopal Tattikota, Yifang Liu, Aram Comjean, Yue Gao, Corey Forman, Grace Kim, Jonathan Rodiger, Irene Papatheodorou, Gilberto Dos Santos, Stephanie Mohr, and Norbert Perrimon. 2021. “DRscDB: A Single-Cell RNA-Seq Resource for Data Mining and Data Comparison across Species”. Comput Struct Biotechnol J, 19, Pp. 2018-26. doi:10.1016/j.csbj.2021.04.021
Yanhui Hu, Sudhir Gopal Tattikota, Yifang Liu, Aram Comjean, Yue Gao, Corey Forman, Grace Kim, Jonathan Rodiger, Irene Papatheodorou, Gilberto Dos Santos, Stephanie Mohr, and Norbert Perrimon. 2021. “DRscDB: A Single-Cell RNA-Seq Resource for Data Mining and Data Comparison across Species”. Comput Struct Biotechnol J, 19, Pp. 2018-26. doi:10.1016/j.csbj.2021.04.021
Yanhui Hu, Aram Comjean, Jonathan Rodiger, Yifang Liu, Yue Gao, Verena Chung, Jonathan Zirin, Norbert Perrimon, and Stephanie Mohr. 2020. “FlyRNAi.Org-the Database of the Drosophila RNAi Screening Center and Transgenic RNAi Project: 2021 Update”. Nucleic Acids Res. doi:10.1093/nar/gkaa936
Yanhui Hu, Aram Comjean, Jonathan Rodiger, Yifang Liu, Yue Gao, Verena Chung, Jonathan Zirin, Norbert Perrimon, and Stephanie Mohr. 2020. “FlyRNAi.Org-the Database of the Drosophila RNAi Screening Center and Transgenic RNAi Project: 2021 Update”. Nucleic Acids Res. doi:10.1093/nar/gkaa936
Yanhui Hu, Verena Chung, Aram Comjean, Jonathan Rodiger, Fnu Nipun, Norbert Perrimon, and Stephanie Mohr. 2020. “BioLitMine: Advanced Mining of Biomedical and Biological Literature About Human Genes and Genes from Major Model Organisms”. G3 (Bethesda). doi:10.1534/g3.120.401775
Yanhui Hu, Verena Chung, Aram Comjean, Jonathan Rodiger, Fnu Nipun, Norbert Perrimon, and Stephanie Mohr. 2020. “BioLitMine: Advanced Mining of Biomedical and Biological Literature About Human Genes and Genes from Major Model Organisms”. G3 (Bethesda). doi:10.1534/g3.120.401775
Hilary Nicholson, Zeshan Tariq, Benjamin Housden, Rebecca Jennings, Laura Stransky, Norbert Perrimon, Sabina Signoretti, and William Kaelin. 2019. “HIF-Independent Synthetic Lethality Between CDK4 6 Inhibition and VHL Loss across Species”. Sci Signal, 12, 601. doi:10.1126/scisignal.aay0482
Hilary Nicholson, Zeshan Tariq, Benjamin Housden, Rebecca Jennings, Laura Stransky, Norbert Perrimon, Sabina Signoretti, and William Kaelin. 2019. “HIF-Independent Synthetic Lethality Between CDK4 6 Inhibition and VHL Loss across Species”. Sci Signal, 12, 601. doi:10.1126/scisignal.aay0482
Stephanie E. Mohr and Norbert Perrimon. 2019. “Drosophila Melanogaster: A Simple System for Understanding Complexity.”. Dis Model Mech, 12, 10
Stephanie E. Mohr and Norbert Perrimon. 2019. “Drosophila Melanogaster: A Simple System for Understanding Complexity.”. Dis Model Mech, 12, 10
Andrey Parkhitko, Patrick Jouandin, Stephanie Mohr, and Norbert Perrimon. 2019. “Methionine Metabolism and Methyltransferases in the Regulation of Aging and Lifespan Extension across Species”. Aging Cell, Pp. e13034. doi:10.1111/acel.13034
Andrey Parkhitko, Patrick Jouandin, Stephanie Mohr, and Norbert Perrimon. 2019. “Methionine Metabolism and Methyltransferases in the Regulation of Aging and Lifespan Extension across Species”. Aging Cell, Pp. e13034. doi:10.1111/acel.13034
Yanhui Hu, Richelle Sopko, Verena Chung, Marianna Foos, Romain Studer, Sean Landry, Daniel Liu, Leonard Rabinow, Florian Gnad, Pedro Beltrao, and Norbert Perrimon. 2019. “IProteinDB: An Integrative Database of Post-Translational Modifications”. G3 (Bethesda), 9, 1, Pp. 1-11. doi:10.1534/g3.118.200637
Yanhui Hu, Richelle Sopko, Verena Chung, Marianna Foos, Romain Studer, Sean Landry, Daniel Liu, Leonard Rabinow, Florian Gnad, Pedro Beltrao, and Norbert Perrimon. 2019. “IProteinDB: An Integrative Database of Post-Translational Modifications”. G3 (Bethesda), 9, 1, Pp. 1-11. doi:10.1534/g3.118.200637
Ben Ewen-Campen, Stephanie Mohr, Yanhui Hu, and Norbert Perrimon. 2017. “Accessing the Phenotype Gap: Enabling Systematic Investigation of Paralog Functional Complexity With CRISPR”. Dev Cell, 43, 1, Pp. 6-9. doi:10.1016/j.devcel.2017.09.020
Ben Ewen-Campen, Stephanie Mohr, Yanhui Hu, and Norbert Perrimon. 2017. “Accessing the Phenotype Gap: Enabling Systematic Investigation of Paralog Functional Complexity With CRISPR”. Dev Cell, 43, 1, Pp. 6-9. doi:10.1016/j.devcel.2017.09.020