Cell-based RNAi

Content tagged with Cell-based RNAi

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Read the DRSC/TRiP Report to the Fly Board 2022

News
Below we share with the community at large the report we provided to the Fly Board in advance of the 2022 Fly Meeting. As always, your feedback on our technologies and services is welcome. We are here to help. DRSC/TRiP Functional Genomics Resources at...

DRSC/TRiP and DRSC-BTRR Office Hours

News
New this fall: Online office hours! Do you have questions about modifying Drosophila cell lines with CRISPR or performing large-scale cell screens? Questions about in vivo RNAi with TRiP fly stocks or CRISPR knockout or activation with our sgRNA fly...

DRSC-Biomedical Technology Research Resource

News
We are pleased to announce that we have been funded by NIH NIGMS to form the Drosophila Research & Screening Center-Biomedical Technology Research Resource (DRSC-BTRR). The P41-funded DRSC-BTRR (N. Perrimon, PI; S. Mohr, Co-I) builds upon and extends past...

DRSC at 17th annual World Preclinical Congress

Event
The DRSC/TRiP-FGR Director, Stephanie Mohr, will be co-teaching a short course on cell-based screening and single-cell studies, as well as co-moderating a discussion session, at the 17th annual World Preclinical Congress.

DRSC & TRiP Workshop at ADRC

Event
The DRSC & TRiP will be hosting a workshop at the Annual Drosophila Research Conference in Philadelphia, PA. The workshop is scheduled for Friday, April 13th from 1:45 to 3:45 PM. Come hear from DRSC & TRiP leaders Norbert Perrimon, Jonathan Zirin...

Bibliographic References tagged with Cell-based RNAi

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Shue Chen, Leah Rosin, Gianluca Pegoraro, Nellie Moshkovich, Patrick Murphy, Guoyun Yu, and Elissa Lei. 2022. “NURF301 Contributes to Gypsy Chromatin Insulator-Mediated Nuclear Organization”. Nucleic Acids Res, 50, 14, Pp. 7906-24. doi:10.1093/nar/gkac600
Shue Chen, Leah Rosin, Gianluca Pegoraro, Nellie Moshkovich, Patrick Murphy, Guoyun Yu, and Elissa Lei. 2022. “NURF301 Contributes to Gypsy Chromatin Insulator-Mediated Nuclear Organization”. Nucleic Acids Res, 50, 14, Pp. 7906-24. doi:10.1093/nar/gkac600
Jiunn Song, Arda Mizrak, Chia-Wei Lee, Marcelo Cicconet, Zon Weng Lai, Wei-Chun Tang, Chieh-Han Lu, Stephanie E. Mohr, Robert V. Farese, and Tobias C. Walther. 2022. “Identification of Two Pathways Mediating Protein Targeting from ER to Lipid Droplets”. Nature Cell Biol
Jiunn Song, Arda Mizrak, Chia-Wei Lee, Marcelo Cicconet, Zon Weng Lai, Wei-Chun Tang, Chieh-Han Lu, Stephanie E. Mohr, Robert V. Farese, and Tobias C. Walther. 2022. “Identification of Two Pathways Mediating Protein Targeting from ER to Lipid Droplets”. Nature Cell Biol
Jiunn Song, Arda Mizrak, Chia-Wei Lee, Marcelo Cicconet, Zon Weng Lai, Chieh-Han Lu, Stephanie E. Mohr, Jr Robert V. Farese, and Tobias C. Walther. 2021. “Identification of Two Pathways Mediating Protein Targeting from ER to Lipid Droplets [NOTE: A Modified Final Version Was Published in Nat Cell Biol and Is Now Available]”
Jiunn Song, Arda Mizrak, Chia-Wei Lee, Marcelo Cicconet, Zon Weng Lai, Chieh-Han Lu, Stephanie E. Mohr, Jr Robert V. Farese, and Tobias C. Walther. 2021. “Identification of Two Pathways Mediating Protein Targeting from ER to Lipid Droplets [NOTE: A Modified Final Version Was Published in Nat Cell Biol and Is Now Available]”
Xiangzhao Yue, Yongkang Liang, Zhishuang Wei, Jun Lv, Yongjin Cai, Xiaobin Fan, Wenqing Zhang, and Jie Chen. 2021. “Genome-Wide in Vitro and in Vivo RNAi Screens Reveal Fer3 to Be an Important Regulator of Kkv Transcription in Drosophila”. Insect Sci. doi:10.1111/1744-7917.12954
Xiangzhao Yue, Yongkang Liang, Zhishuang Wei, Jun Lv, Yongjin Cai, Xiaobin Fan, Wenqing Zhang, and Jie Chen. 2021. “Genome-Wide in Vitro and in Vivo RNAi Screens Reveal Fer3 to Be an Important Regulator of Kkv Transcription in Drosophila”. Insect Sci. doi:10.1111/1744-7917.12954
Yanhui Hu, Aram Comjean, Jonathan Rodiger, Yifang Liu, Yue Gao, Verena Chung, Jonathan Zirin, Norbert Perrimon, and Stephanie Mohr. 2020. “FlyRNAi.Org-the Database of the Drosophila RNAi Screening Center and Transgenic RNAi Project: 2021 Update”. Nucleic Acids Res. doi:10.1093/nar/gkaa936
Yanhui Hu, Aram Comjean, Jonathan Rodiger, Yifang Liu, Yue Gao, Verena Chung, Jonathan Zirin, Norbert Perrimon, and Stephanie Mohr. 2020. “FlyRNAi.Org-the Database of the Drosophila RNAi Screening Center and Transgenic RNAi Project: 2021 Update”. Nucleic Acids Res. doi:10.1093/nar/gkaa936
Hilary Nicholson, Zeshan Tariq, Benjamin Housden, Rebecca Jennings, Laura Stransky, Norbert Perrimon, Sabina Signoretti, and William Kaelin. 2019. “HIF-Independent Synthetic Lethality Between CDK4 6 Inhibition and VHL Loss across Species”. Sci Signal, 12, 601. doi:10.1126/scisignal.aay0482
Hilary Nicholson, Zeshan Tariq, Benjamin Housden, Rebecca Jennings, Laura Stransky, Norbert Perrimon, Sabina Signoretti, and William Kaelin. 2019. “HIF-Independent Synthetic Lethality Between CDK4 6 Inhibition and VHL Loss across Species”. Sci Signal, 12, 601. doi:10.1126/scisignal.aay0482
Spencer E. Escobedo, Jonathan Zirin, and Vikki M. Weake. 2019. “TRiP Stocks Contain a Previously Uncharacterized Loss-of-Function Sevenless Allele”. MicroPublication Biology
Spencer E. Escobedo, Jonathan Zirin, and Vikki M. Weake. 2019. “TRiP Stocks Contain a Previously Uncharacterized Loss-of-Function Sevenless Allele”. MicroPublication Biology
Hirotaka Kanoh, Li-Li Tong, Takayuki Kuraishi, Yamato Suda, Yoshiki Momiuchi, Fumi Shishido, and Shoichiro Kurata. 2015. “Genome-Wide RNAi Screening Implicates the E3 Ubiquitin Ligase Sherpa in Mediating Innate Immune Signaling by Toll in Drosophila Adults”. Sci Signal, 8, 400, Pp. ra107. doi:10.1126/scisignal.2005971
Hirotaka Kanoh, Li-Li Tong, Takayuki Kuraishi, Yamato Suda, Yoshiki Momiuchi, Fumi Shishido, and Shoichiro Kurata. 2015. “Genome-Wide RNAi Screening Implicates the E3 Ubiquitin Ligase Sherpa in Mediating Innate Immune Signaling by Toll in Drosophila Adults”. Sci Signal, 8, 400, Pp. ra107. doi:10.1126/scisignal.2005971
Hirotaka Kanoh, Takayuki Kuraishi, Li-Li Tong, Ryo Watanabe, Shinji Nagata, and Shoichiro Kurata. 2015. “Ex Vivo Genome-Wide RNAi Screening of the Drosophila Toll Signaling Pathway Elicited by a Larva-Derived Tissue Extract”. Biochem Biophys Res Commun, 467, 2, Pp. 400-6. doi:10.1016/j.bbrc.2015.09.138
Hirotaka Kanoh, Takayuki Kuraishi, Li-Li Tong, Ryo Watanabe, Shinji Nagata, and Shoichiro Kurata. 2015. “Ex Vivo Genome-Wide RNAi Screening of the Drosophila Toll Signaling Pathway Elicited by a Larva-Derived Tissue Extract”. Biochem Biophys Res Commun, 467, 2, Pp. 400-6. doi:10.1016/j.bbrc.2015.09.138
Stephanie Mohr, Kirstin Rudd, Yanhui Hu, Wei Song, Quentin Gilly, Michael Buckner, Benjamin Housden, Colleen Kelley, Jonathan Zirin, Rong Tao, Gabriel Amador, Katarzyna Sierzputowska, Aram Comjean, and Norbert Perrimon. 2017. “Zinc Detoxification: A Functional Genomics and Transcriptomics Analysis in Drosophila Melanogaster Cultured Cells”. G3 (Bethesda). doi:10.1534/g3.117.300447
Stephanie Mohr, Kirstin Rudd, Yanhui Hu, Wei Song, Quentin Gilly, Michael Buckner, Benjamin Housden, Colleen Kelley, Jonathan Zirin, Rong Tao, Gabriel Amador, Katarzyna Sierzputowska, Aram Comjean, and Norbert Perrimon. 2017. “Zinc Detoxification: A Functional Genomics and Transcriptomics Analysis in Drosophila Melanogaster Cultured Cells”. G3 (Bethesda). doi:10.1534/g3.117.300447