Disease-related studies

Content tagged with Disease-related studies

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DRSC/TRiP and DRSC-BTRR Office Hours

News
New this fall: Online office hours! Do you have questions about modifying Drosophila cell lines with CRISPR or performing large-scale cell screens? Questions about in vivo RNAi with TRiP fly stocks or CRISPR knockout or activation with our sgRNA fly...

New publications from the DRSC bioinformatics team

News
The DRSC bioinformatics team, led by Dr. Claire Yanhui Hu, has recently published two new papers. One reports development of BioLitMine, an advanced literature mining resource. The other provides an overview of our online resources, which can be grouped...

DRSC-Biomedical Technology Research Resource

News
We are pleased to announce that we have been funded by NIH NIGMS to form the Drosophila Research & Screening Center-Biomedical Technology Research Resource (DRSC-BTRR). The P41-funded DRSC-BTRR (N. Perrimon, PI; S. Mohr, Co-I) builds upon and extends past...

DRSC Bioinformatics launches iProteinDB and BioLitMine

News
We have two new online tools available: iProteinDB and BioLitMine. Both continue our series of resources aimed at integrating existing information in new ways to facilitate data mining and development of new hypotheses. In addition, iProteinDB includes a...

Community Building and Online Resources at the DRSC/TRiP

News
At the DRSC/TRiP-Functional Genomics Resources, we are interested to let the community know about new resources we have built. We are also interested more broadly to help connect community members to additional resources that could help their research...

Director S. Mohr presents at the Countway Longwood Author Series

Event
On June 18th, DRSC/TRiP-FGR Director Dr. Stephanie Mohr will present an introduction to Drosophila research and discuss her book First in Fly: Drosophila Research and Biological Discussion, as part of the Countway Longwood Author Series. The event will be...

DRSC & TRiP Workshop at ADRC

Event
The DRSC & TRiP will be hosting a workshop at the Annual Drosophila Research Conference in Philadelphia, PA. The workshop is scheduled for Friday, April 13th from 1:45 to 3:45 PM. Come hear from DRSC & TRiP leaders Norbert Perrimon, Jonathan Zirin...

Now Available: Our 2017 NAR database issue update

News
Read about the DRSC/TRiP Functional Genomics Resources online tools and more in our 2017 Nucleic Acids Research database issue update publication. Tables 1 & 2 in particular are meant to give you a quick look at what online tools we offer and how they fit...

DRSC & TRiP at TAGC 2016

News
We have begun preparing for our participation at TAGC 2016 in Orlando, FL. We will be presenting a workshop on functional genomics for cross-species studies, as well as participating in the poster session. Want to talk with experts in cell or in vivo RNAi...

Bibliographic References tagged with Disease-related studies

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Hans M. Dalton, Raghuvir Viswanatha, Ricky Brathwaite Jr., Jae Sophia Zuno, Stephanie Mohr, Norbert Perrimon, and Clement Y. Chow. 2021. “A Genome-Wide CRISPR Screen Identifies the Glycosylation Enzyme DPM1 As a Modifier of DPAGT1 Deficiency and ER Stress”. BioRxiv
Hans M. Dalton, Raghuvir Viswanatha, Ricky Brathwaite Jr., Jae Sophia Zuno, Stephanie Mohr, Norbert Perrimon, and Clement Y. Chow. 2021. “A Genome-Wide CRISPR Screen Identifies the Glycosylation Enzyme DPM1 As a Modifier of DPAGT1 Deficiency and ER Stress”. BioRxiv
Raghuvir Viswanatha, Enzo Mameli, Jonathan Rodiger, Pierre Merckaert, Fabiana Feitosa-Suntheimer, Tonya Colpitts, Stephanie Mohr, Yanhui Hu, and Norbert Perrimon. 2021. “Bioinformatic and Cell-Based Tools for Pooled CRISPR Knockout Screening in Mosquitos”. Nat Commun, 12, 1, Pp. 6825. doi:10.1038/s41467-021-27129-3
Raghuvir Viswanatha, Enzo Mameli, Jonathan Rodiger, Pierre Merckaert, Fabiana Feitosa-Suntheimer, Tonya Colpitts, Stephanie Mohr, Yanhui Hu, and Norbert Perrimon. 2021. “Bioinformatic and Cell-Based Tools for Pooled CRISPR Knockout Screening in Mosquitos”. Nat Commun, 12, 1, Pp. 6825. doi:10.1038/s41467-021-27129-3
Yanhui Hu, Aram Comjean, Jonathan Rodiger, Yifang Liu, Yue Gao, Verena Chung, Jonathan Zirin, Norbert Perrimon, and Stephanie Mohr. 2020. “FlyRNAi.Org-the Database of the Drosophila RNAi Screening Center and Transgenic RNAi Project: 2021 Update”. Nucleic Acids Res. doi:10.1093/nar/gkaa936
Yanhui Hu, Aram Comjean, Jonathan Rodiger, Yifang Liu, Yue Gao, Verena Chung, Jonathan Zirin, Norbert Perrimon, and Stephanie Mohr. 2020. “FlyRNAi.Org-the Database of the Drosophila RNAi Screening Center and Transgenic RNAi Project: 2021 Update”. Nucleic Acids Res. doi:10.1093/nar/gkaa936
Yanhui Hu, Verena Chung, Aram Comjean, Jonathan Rodiger, Fnu Nipun, Norbert Perrimon, and Stephanie Mohr. 2020. “BioLitMine: Advanced Mining of Biomedical and Biological Literature About Human Genes and Genes from Major Model Organisms”. G3 (Bethesda). doi:10.1534/g3.120.401775
Yanhui Hu, Verena Chung, Aram Comjean, Jonathan Rodiger, Fnu Nipun, Norbert Perrimon, and Stephanie Mohr. 2020. “BioLitMine: Advanced Mining of Biomedical and Biological Literature About Human Genes and Genes from Major Model Organisms”. G3 (Bethesda). doi:10.1534/g3.120.401775
Stephanie E. Mohr and Norbert Perrimon. 2019. “Drosophila Melanogaster: A Simple System for Understanding Complexity.”. Dis Model Mech, 12, 10
Stephanie E. Mohr and Norbert Perrimon. 2019. “Drosophila Melanogaster: A Simple System for Understanding Complexity.”. Dis Model Mech, 12, 10
Andrey Parkhitko, Patrick Jouandin, Stephanie Mohr, and Norbert Perrimon. 2019. “Methionine Metabolism and Methyltransferases in the Regulation of Aging and Lifespan Extension across Species”. Aging Cell, Pp. e13034. doi:10.1111/acel.13034
Andrey Parkhitko, Patrick Jouandin, Stephanie Mohr, and Norbert Perrimon. 2019. “Methionine Metabolism and Methyltransferases in the Regulation of Aging and Lifespan Extension across Species”. Aging Cell, Pp. e13034. doi:10.1111/acel.13034
Yanhui Hu, Aram Comjean, Stephanie Mohr, The FlyBase Consortium, and Norbert Perrimon. 2017. “Gene2Function: An Integrated Online Resource for Gene Function Discovery”. G3 (Bethesda). doi:10.1534/g3.117.043885
Yanhui Hu, Aram Comjean, Stephanie Mohr, The FlyBase Consortium, and Norbert Perrimon. 2017. “Gene2Function: An Integrated Online Resource for Gene Function Discovery”. G3 (Bethesda). doi:10.1534/g3.117.043885
2015. “MitoMax Data Set and Annotations (data Portal for Chen et Al. 2015 ‘Proteomic Mapping in Live Drosophila Tissues Using an Engineeredascorbate Peroxidase,’ Proc Natl Acad Sci U S A. Vol. 112(39):12093-8. PMID: 26362788; PMCID: PMC4593093.)”
2015. “MitoMax Data Set and Annotations (data Portal for Chen et Al. 2015 ‘Proteomic Mapping in Live Drosophila Tissues Using an Engineeredascorbate Peroxidase,’ Proc Natl Acad Sci U S A. Vol. 112(39):12093-8. PMID: 26362788; PMCID: PMC4593093.)”
Arunachalam Vinayagam, Meghana Kulkarni, Richelle Sopko, Xiaoyun Sun, Yanhui Hu, Ankita Nand, Christians Villalta, Ahmadali Moghimi, Xuemei Yang, Stephanie Mohr, Pengyu Hong, John Asara, and Norbert Perrimon. 2016. “An Integrative Analysis of the InR PI3K Akt Network Identifies the Dynamic Response to Insulin Signaling”. Cell Reports, 16, 11, Pp. 3062-74
Arunachalam Vinayagam, Meghana Kulkarni, Richelle Sopko, Xiaoyun Sun, Yanhui Hu, Ankita Nand, Christians Villalta, Ahmadali Moghimi, Xuemei Yang, Stephanie Mohr, Pengyu Hong, John Asara, and Norbert Perrimon. 2016. “An Integrative Analysis of the InR PI3K Akt Network Identifies the Dynamic Response to Insulin Signaling”. Cell Reports, 16, 11, Pp. 3062-74
Jennifer Philips, Eric Rubin, and Norbert Perrimon. 2005. “Drosophila RNAi Screen Reveals CD36 Family Member Required for Mycobacterial Infection.”. Science, 309, 5738, Pp. 1251-3. doi:10.1126/science.1116006
Jennifer Philips, Eric Rubin, and Norbert Perrimon. 2005. “Drosophila RNAi Screen Reveals CD36 Family Member Required for Mycobacterial Infection.”. Science, 309, 5738, Pp. 1251-3. doi:10.1126/science.1116006