Disease models

Content tagged with Disease models

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DRSC/TRiP and DRSC-BTRR Office Hours

News
New this fall: Online office hours! Do you have questions about modifying Drosophila cell lines with CRISPR or performing large-scale cell screens? Questions about in vivo RNAi with TRiP fly stocks or CRISPR knockout or activation with our sgRNA fly...

DRSC Bioinformatics launches iProteinDB and BioLitMine

News
We have two new online tools available: iProteinDB and BioLitMine. Both continue our series of resources aimed at integrating existing information in new ways to facilitate data mining and development of new hypotheses. In addition, iProteinDB includes a...

Community Building and Online Resources at the DRSC/TRiP

News
At the DRSC/TRiP-Functional Genomics Resources, we are interested to let the community know about new resources we have built. We are also interested more broadly to help connect community members to additional resources that could help their research...

Director S. Mohr presents at the Countway Longwood Author Series

Event
On June 18th, DRSC/TRiP-FGR Director Dr. Stephanie Mohr will present an introduction to Drosophila research and discuss her book First in Fly: Drosophila Research and Biological Discussion, as part of the Countway Longwood Author Series. The event will be...

DRSC & TRiP Workshop at ADRC

Event
The DRSC & TRiP will be hosting a workshop at the Annual Drosophila Research Conference in Philadelphia, PA. The workshop is scheduled for Friday, April 13th from 1:45 to 3:45 PM. Come hear from DRSC & TRiP leaders Norbert Perrimon, Jonathan Zirin...

Now Available: Our 2017 NAR database issue update

News
Read about the DRSC/TRiP Functional Genomics Resources online tools and more in our 2017 Nucleic Acids Research database issue update publication. Tables 1 & 2 in particular are meant to give you a quick look at what online tools we offer and how they fit...

Bibliographic References tagged with Disease models

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Yanhui Hu, Ian Flockhart, Arunachalam Vinayagam, Clemens Bergwitz, Bonnie Berger, Norbert Perrimon, and Stephanie Mohr. 2011. “An Integrative Approach to Ortholog Prediction for Disease-Focused and Other Functional Studies.”. BMC Bioinformatics, 12, Pp. 357. doi:10.1186/1471-2105-12-357
Yanhui Hu, Ian Flockhart, Arunachalam Vinayagam, Clemens Bergwitz, Bonnie Berger, Norbert Perrimon, and Stephanie Mohr. 2011. “An Integrative Approach to Ortholog Prediction for Disease-Focused and Other Functional Studies.”. BMC Bioinformatics, 12, Pp. 357. doi:10.1186/1471-2105-12-357
Joost Schulte, Katharine Sepp, Chaohong Wu, Pengyu Hong, and Troy Littleton. 2011. “High-Content Chemical and RNAi Screens for Suppressors of Neurotoxicity in a Huntington’s Disease Model.”. PLoS One, 6, 8, Pp. e23841. doi:10.1371/journal.pone.0023841
Joost Schulte, Katharine Sepp, Chaohong Wu, Pengyu Hong, and Troy Littleton. 2011. “High-Content Chemical and RNAi Screens for Suppressors of Neurotoxicity in a Huntington’s Disease Model.”. PLoS One, 6, 8, Pp. e23841. doi:10.1371/journal.pone.0023841
Keren Imberg-Kazdan, Susan Ha, Alex Greenfield, Christopher Poultney, Richard Bonneau, Susan Logan, and Michael Garabedian. 2013. “A Genome-Wide RNA Interference Screen Identifies New Regulators of Androgen Receptor Function in Prostate Cancer Cells.”. Genome Res, 23, 4, Pp. 581-91. doi:10.1101/gr.144774.112
Keren Imberg-Kazdan, Susan Ha, Alex Greenfield, Christopher Poultney, Richard Bonneau, Susan Logan, and Michael Garabedian. 2013. “A Genome-Wide RNA Interference Screen Identifies New Regulators of Androgen Receptor Function in Prostate Cancer Cells.”. Genome Res, 23, 4, Pp. 581-91. doi:10.1101/gr.144774.112
Joshua Shulman, Selina Imboywa, Nikolaos Giagtzoglou, Martin Powers, Yanhui Hu, Danelle Devenport, Portia Chipendo, Lori Chibnik, Allison Diamond, Norbert Perrimon, Nicholas Brown, Philip De Jager, and Mel Feany. 2014. “Functional Screening in Drosophila Identifies Alzheimer’s Disease Susceptibility Genes and Implicates Tau-Mediated Mechanisms.”. Hum Mol Genet, 23, 4, Pp. 870-7. doi:10.1093/hmg/ddt478
Joshua Shulman, Selina Imboywa, Nikolaos Giagtzoglou, Martin Powers, Yanhui Hu, Danelle Devenport, Portia Chipendo, Lori Chibnik, Allison Diamond, Norbert Perrimon, Nicholas Brown, Philip De Jager, and Mel Feany. 2014. “Functional Screening in Drosophila Identifies Alzheimer’s Disease Susceptibility Genes and Implicates Tau-Mediated Mechanisms.”. Hum Mol Genet, 23, 4, Pp. 870-7. doi:10.1093/hmg/ddt478
Benjamin Housden, Alexander Valvezan, Colleen Kelley, Richelle Sopko, Yanhui Hu, Charles Roesel, Shuailiang Lin, Michael Buckner, Rong Tao, Bahar Yilmazel, Stephanie Mohr, Brendan Manning, and Norbert Perrimon. 2015. “Identification of Potential Drug Targets for Tuberous Sclerosis Complex by Synthetic Screens Combining CRISPR-Based Knockouts With RNAi.”. Sci Signal, 8, 393, Pp. rs9. doi:10.1126/scisignal.aab3729
Benjamin Housden, Alexander Valvezan, Colleen Kelley, Richelle Sopko, Yanhui Hu, Charles Roesel, Shuailiang Lin, Michael Buckner, Rong Tao, Bahar Yilmazel, Stephanie Mohr, Brendan Manning, and Norbert Perrimon. 2015. “Identification of Potential Drug Targets for Tuberous Sclerosis Complex by Synthetic Screens Combining CRISPR-Based Knockouts With RNAi.”. Sci Signal, 8, 393, Pp. rs9. doi:10.1126/scisignal.aab3729