Online tools

Used our tools in a study? Please cite Hu et al. (2025) NAR Database Issue and individual tool publications.

Multi-Species

DIOPT ortholog search
10 species, 18 algorithms
[Demo Video]

Gene2Function
orthologs & gene info summaries (orthologs, GO, & more)
[Demo Video]

BioLitMine
literature mining tool (genes, pathways, people, MeSH terms)
[Demo Video]

MIST
protein-protein & genetic interactions
(multi-source)
[Demo Video]

(PAthway, Network and Gene-set Enrichment Analysis)

Fly CRISPR

Fly PTMs

Square icon for fly sgRNA database and LIMS

TRiP sgRNA LIMS
nominate or track TRiP-KO & -OE fly stock production

Square icon for Find CRISPRs online resource

Find CRISPRs
fly sgRNA designs with genome view
(2017 version)

CRISPR3

Find CRISPRs 3
fly sgRNA designs with genome view
(2019 version)
[Demo Video]

SNP CRISPR
design allele-specific sgRNA for major model organisms

iProteinDB
post-translational modifications
[Demo Video]

Fly RNAi

UP-TORR
cell and in vivo RNAi reagent search

SnapDragon
design dsRNAs for
fly cell RNAi
[Demo Video]

RSVP Plus
in vivo CRISPR & RNAi phenotype data

Screen Summary
browse DRSC cell RNAi screen data sets

GeneLookup
(search DRSC & TRiP reagents by gene)

TRiP Batch Query
(make a TRiP fly stock list from a gene list)

RNASeq/ scRNASeq
Resources

More fly resources

DGET
mine bulk RNAseq data for fly

DRscDB single-cell portal

GLAD
view grouped gene lists for fly

FlyPrimerBank
find qPCR primers
for fly studies
[Demo Video]

Paralogs Explorer
find paralogs & info

More fly resource and utility tools

Cell Line Expression

List of Utility Tools

Network & Pathway

Transcription Factor-Target Gene Analyses

COMPLEAT
protein complex enrichment analysis
(fly, human, yeast)
[Demo Video]

FlyPredictome Data Portal

Flyphone
predict cell-cell communication from scRNAseq data

Screenshot from the PathOn online resource home page

PathOn
find pathway status in your RNAseq data

Data Sets

List of Data Sets
(DRSC & Perrimon)
with links

Single-cell RNAseq data sets for specific tissues

InsulinNet fly PPI, RNAi, PTM data
Vinayagam et al.

MitoMax fly mitochondrial proteomics data set
Chen et al.

PhosphoSite fly kinase network data set
Sopko et al.

Pooled CRISPR fly cell screen raw data sets
Viswanatha et al.

Nucleolar fly cell RNAi image-based screen data set
Neumuller et al.

DRSC RNA Binding RNAi library fly cell screen data set
Mohr et al.

Table of all public DRSC cell-based RNAi screen data sets at Screen Summary

FlyBi Drosophila Y2H binary interaction data DRSC/CCSB/BDGP

Mosquito resources

Other

Ortholog Mapping
(D. mel <-> mosquitos)
[Demo Video]

CRISPR sgRNA designs
(mosquitos)
[Demo Video]

MARRVEL
Connect human gene variants to ortholog info (multi-source)

DIOPT-DIST
Connect disease genes to ortholog info or vice versa (OMIM & GWAS)

InsulinNet
fly insulin network data (PPI, RNAi, PTM +/- insulin)
[Demo Video]

CRIMIC
nominate for GDP gene trap fly stocks -->

Signed PPI/

DirectedPPI

No Longer available.

CONTACT US

report a bug or make a suggestion

NOTE: Due to a planned institutional IT hardware move, DRSC online tools might not be reachable or functional during part or all of the period January 3 - January 10, 2025. Thank you for your understanding.

Citations help us keep going

Be sure to cite our online resources if they contribute to a published study. You can cite our latest Nucleic Acids Research Database Issue paper and/or the publication(s) corresponding to the specific online resource(s) that you used. Please see our publications page.