Recent News

Image of green fluorescence in GFP-tagged Drosophila cultured cells

New cell lines & new understandings using cutting-edge techniques

February 2, 2024

As a facility that supports large-scale screens in Drosophila and other insect cell lines, we get excited about reports of new Drosophila cell lines and related info.

We'd like to highlight two recent papers.

One report, a collaboration between Amanda Simcox's group, the DGRC, and our group here at the DRSC, describes new cell lines made in Amanda's group and characterized in a collaboration of the three groups. Muscle cells that pulse? Yes. That and other exciting new cell lines are reported in the publication below, and the cells are available at the DGRC...

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Figure 1 from Xu, Kim et al 2022 in eLife

Light up your flies! Reagent and protocol information for application of our NanoTag system for epitope tagging in Drosophila

March 23, 2023

One of the areas of interest for our technology development group is nanobodies. These small, single-chain antibodies are particularly attractive for Drosophila research as in addition to being used for standard immune-technologies such as immunoblots and immunostaining of tissues, they can also be expressed in vivo as fusions to fluorescent proteins (‘chromobodies’) or functional domains (e.g., for degradation or re-localization).

Past applications of this technology in Drosophila relied on availability of nanobodies targeting a specific protein or use of nanobodies targeting...

Read more about Light up your flies! Reagent and protocol information for application of our NanoTag system for epitope tagging in Drosophila
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