Online tools

Used our tools in a study? Please cite Hu et al. (2025) NAR Database Issue and individual tool publications. Newly added tools are shown in bold.

Multi-Species

DIOPT

search ortholog in major MODs
[Demo Video]

DIOPT_Arthropod

search ortholog in arthropod

Gene2Function
orthologs & gene info summaries (orthologs, GO, & more)
[Demo Video]

BioLitMine
literature mining tool (genes, pathways, people, MeSH terms)
[Demo Video]

MIST
protein-protein & genetic interactions
(multi-source)
[Demo Video]

PANGEA

(PAthway, Network and Gene-set Enrichment Analysis)

Fly CRISPR

Fly PTMs

Square icon for fly sgRNA database and LIMS

TRiP sgRNA LIMS
nominate or track TRiP-KO & -OE fly stock production

Square icon for Find CRISPRs online resource

Find CRISPRs
fly sgRNA designs with genome view
(2017 version)

Find CRISPRs 3
fly sgRNA designs with genome view
(2019 version)
[Demo Video]

SNP CRISPR
design allele-specific sgRNA for major model organisms

iProteinDB
post-translational modifications
[Demo Video]

RNASeq/ scRNASeq
Resources

More fly resources

DGET
mine bulk RNAseq data for fly

Perrimon scRNAseq atlas

DRscDB single-cell portal

FlyAnatoView

View scRNA-seq data on anatomograph

GLAD
view fly gene lists

Fly Secretome

Mine/browse secreted proteins

FlyPrimerBank
find qPCR primers
for fly studies
[Demo Video]

Paralogs Explorer
find paralogs & info

Others:

Cell Line Expression

List of Utility Tools

Network & Pathway

Transcription Factor-Target Gene Analyses

COMPLEAT
protein complex analysis
[Demo Video]

COMPLEAT2 (updated, more species)

FlyPredictome Data Portal

FlyPhone
predict cell-cell communication from scRNAseq data

FlyPhone2

(updated)

Screenshot from the PathOn online resource home page

PathOn
find pathway status in your RNAseq data

TF2TG

Fly RNAi

UP-TORR
cell and in vivo RNAi reagent search

RSVP Plus
in vivo CRISPR & RNAi phenotype data

SnapDragon
design dsRNAs for
fly cell RNAi
[Demo Video]

Screen Summary
browse DRSC cell RNAi screen data sets

GeneLookup
(search DRSC & TRiP reagents by gene)

TRiP Batch Query
(make a TRiP fly stock list from a gene list)

Data Sets

List of Data Sets
(DRSC & Perrimon)
with links

Single-cell RNAseq data sets for specific tissues

InsulinNet fly PPI, RNAi, PTM data
Vinayagam et al.

MitoMax fly mitochondrial proteomics data set
Chen et al.

PhosphoSite fly kinase network data set
Sopko et al.

Pooled CRISPR fly cell screen raw data sets
Viswanatha et al.

Nucleolar fly cell RNAi image-based screen data set
Neumuller et al.

DRSC RNA Binding RNAi library fly cell screen data set
Mohr et al.

Table of all public DRSC cell-based RNAi screen data sets at Screen Summary

FlyBi Drosophila Y2H binary interaction data DRSC/CCSB/BDGP

Mosquito resources

Other

Ortholog Mapping
(D. mel <-> mosquitos)
[Demo Video]

CRISPR sgRNA designs
(mosquitos)
[Demo Video]

MARRVEL
Connect human gene variants to ortholog info (multi-source)

DIOPT-DIST
Connect disease genes to ortholog info or vice versa (OMIM & GWAS)

InsulinNet
fly insulin network data (PPI, RNAi, PTM +/- insulin)
[Demo Video]

No longer available:

Signed PPI

DirectedPPI

CRIMIC

report a bug or make a suggestion

NOTE: Due to a planned institutional IT hardware move, DRSC online tools might not be reachable or functional during part or all of the period January 3 - January 10, 2025. Thank you for your understanding.

Citations help us keep going

Be sure to cite our online resources if they contribute to a published study. You can cite our latest Nucleic Acids Research Database Issue paper and/or the publication(s) corresponding to the specific online resource(s) that you used. Please see our publications page.