Online tools

Used our tools in a study? Please cite Hu et al. (2025) NAR Database Issue and individual tool publications. Newly added tools are shown in bold.
Multi-Species
DIOPT search ortholog in major MODs [Demo Video] DIOPT_Arthropod search ortholog in arthropod	Gene2Function orthologs & gene info summaries (orthologs, GO, & more) [Demo Video]	BioLitMine literature mining tool (genes, pathways, people, MeSH terms) [Demo Video]	MIST protein-protein & genetic interactions (multi-source) [Demo Video]	PANGEA (PAthway, Network and Gene-set Enrichment Analysis)
Fly CRISPR			Arthropod CRISPR	Fly PTMs
TRiP sgRNA LIMS nominate or track TRiP-KO & -OE fly stock production	fly sgRNA with genome view [Demo Video] Find CRISPRs (vs 2017) Find CRISPRs 3 (vs 2019)	SNP CRISPR design allele-specific sgRNA for major model organisms	GuideXpress sgRNA with genome view for mosquito, tick and moth	iProteinDB post-translational modifications [Demo Video]
RNASeq/ scRNASeq Resources		More fly resources
DGET mine bulk RNAseq data for fly Perrimon scRNAseq atlas	DRscDB single-cell portal FlyAnatoView View scRNA-seq data on anatomograph	GLAD view fly gene lists Fly Secretome Mine/browse secreted proteins	FlyPrimerBank find qPCR primers for fly studies [Demo Video]	Paralogs Explorer find paralogs & info Others: Cell Line Expression List of Utility Tools
Network & Pathway				Transcription regulation
COMPLEAT protein complex analysis [Demo Video] COMPLEAT2 (updated, more species)	FlyPredictome Data Portal	FlyPhone predict cell-cell communication from scRNAseq data FlyPhone2 (updated)	PathOn find pathway status in your RNAseq data	TF2TG find the transcription factors for input gene or the gene targets for input TF
Fly RNAi
UP-TORR cell and in vivo RNAi reagent search	RSVP Plus in vivo CRISPR & RNAi phenotype data	SnapDragon design dsRNAs for fly cell RNAi [Demo Video]	Screen Summary browse DRSC cell RNAi screen data sets	GeneLookup (search DRSC & TRiP reagents by gene) TRiP Batch Query (make a TRiP fly stock list from a gene list)
Data Sets
List of Data Sets (DRSC & Perrimon) with links	Single-cell RNAseq data sets for specific tissues	InsulinNet fly PPI, RNAi, PTM data Vinayagam et al.	MitoMax fly mitochondrial proteomics data set Chen et al.	PhosphoSite fly kinase network data set Sopko et al.
Pooled CRISPR fly cell screen raw data sets Viswanatha et al.	Nucleolar fly cell RNAi image-based screen data set Neumuller et al.	DRSC RNA Binding RNAi library fly cell screen data set Mohr et al.	Table of all public DRSC cell-based RNAi screen data sets at Screen Summary	FlyBi Drosophila Y2H binary interaction data DRSC/CCSB/BDGP
Mosquito resources		Other
Ortholog Mapping (D. mel <-> mosquitos) [Demo Video]	CRISPR sgRNA designs (mosquitos) [Demo Video]	MARRVEL Connect human gene variants to ortholog info (multi-source) DIOPT-DIST Connect disease genes to ortholog info or vice versa (OMIM & GWAS)	InsulinNet fly insulin network data (PPI, RNAi, PTM +/- insulin) [Demo Video]	No longer available: Signed PPI DirectedPPI CRIMIC

report a bug or make a suggestion

NOTE: Due to a planned institutional IT hardware move, DRSC online tools might not be reachable or functional during part or all of the period January 3 - January 10, 2025. Thank you for your understanding.

Citations help us keep going

Be sure to cite our online resources if they contribute to a published study. You can cite our latest Nucleic Acids Research Database Issue paper and/or the publication(s) corresponding to the specific online resource(s) that you used. Please see our publications page.