Essential genes
Content tagged with Essential genes
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News
At the DRSC-BTRR, we've been doing a lot of pooled-format CRISPR knockout screens in Drosophila cells. We're finding the results to be robust and reproducible. And best of all, the results have been informative, providing insights into diverse areas of...
Pooled-format CRISPR screens in Drosophila cells
News
The DRSC/TRiP-FGR is pleased to support collaborations on pooled CRISPR screens using the method recently, reported in eLife by Viswanatha et al. (PDF download file below). From the abstract: "... Here, we developed a site-specific integration strategy...
DRSC & TRiP Workshop at ADRC
Event
The DRSC & TRiP will be hosting a workshop at the Annual Drosophila Research Conference in Philadelphia, PA. The workshop is scheduled for Friday, April 13th from 1:45 to 3:45 PM. Come hear from DRSC & TRiP leaders Norbert Perrimon, Jonathan Zirin...
Bibliographic References tagged with Essential genes
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Enzo Mameli, George-Rafael Samantsidis, Raghuvir Viswanatha, Hyeogsun Kwon, David R Hall, Matthew Butnaru, Yanhui Hu, Stephanie E Mohr, Norbert Perrimon, and Ryan C Smith. 2024. “A Genome-Wide CRISPR Screen in Mosquito Cells Identifies Essential Genes and Required Components of Clodronate Liposome Function.”. BioRxiv : The Preprint Server for Biology. doi:10.1101/2024.09.24.614595
Enzo Mameli, George-Rafael Samantsidis, Raghuvir Viswanatha, Hyeogsun Kwon, David R Hall, Matthew Butnaru, Yanhui Hu, Stephanie E Mohr, Norbert Perrimon, and Ryan C Smith. 2024. “A Genome-Wide CRISPR Screen in Mosquito Cells Identifies Essential Genes and Required Components of Clodronate Liposome Function.”. BioRxiv : The Preprint Server for Biology. doi:10.1101/2024.09.24.614595
Raghuvir Viswanatha, Samuel Entwisle, Claire Hu, Kelly Reap, Matthew Butnaru, Stephanie E Mohr, and Norbert Perrimon. 2024. “Higher Resolution Pooled Genome-Wide CRISPR Knockout Screening in Drosophila Cells Using Integration and Anti-CRISPR (IntAC).”. BioRxiv : The Preprint Server for Biology. doi:10.1101/2024.09.19.613976
Raghuvir Viswanatha, Samuel Entwisle, Claire Hu, Kelly Reap, Matthew Butnaru, Stephanie E Mohr, and Norbert Perrimon. 2024. “Higher Resolution Pooled Genome-Wide CRISPR Knockout Screening in Drosophila Cells Using Integration and Anti-CRISPR (IntAC).”. BioRxiv : The Preprint Server for Biology. doi:10.1101/2024.09.19.613976
Raghuvir Viswanatha, Roderick Brathwaite, Yanhui Hu, Zhongchi Li, Jonathan Rodiger, Pierre Merckaert, Verena Chung, Stephanie Mohr, and Norbert Perrimon. 2019. “Pooled CRISPR Screens in Drosophila Cells”. Curr Protoc Mol Biol, 129, 1, Pp. e111. doi:10.1002/cpmb.111
Raghuvir Viswanatha, Roderick Brathwaite, Yanhui Hu, Zhongchi Li, Jonathan Rodiger, Pierre Merckaert, Verena Chung, Stephanie Mohr, and Norbert Perrimon. 2019. “Pooled CRISPR Screens in Drosophila Cells”. Curr Protoc Mol Biol, 129, 1, Pp. e111. doi:10.1002/cpmb.111
Ben Ewen-Campen, Stephanie Mohr, Yanhui Hu, and Norbert Perrimon. 2017. “Accessing the Phenotype Gap: Enabling Systematic Investigation of Paralog Functional Complexity With CRISPR”. Dev Cell, 43, 1, Pp. 6-9. doi:10.1016/j.devcel.2017.09.020
Ben Ewen-Campen, Stephanie Mohr, Yanhui Hu, and Norbert Perrimon. 2017. “Accessing the Phenotype Gap: Enabling Systematic Investigation of Paralog Functional Complexity With CRISPR”. Dev Cell, 43, 1, Pp. 6-9. doi:10.1016/j.devcel.2017.09.020
Michael Boutros, Amy Kiger, Susan Armknecht, Kim Kerr, Marc Hild, Britta Koch, Stefan Haas, Renato Paro, Norbert Perrimon, and Heidelberg Fly Array Consortium. 2004. “Genome-Wide RNAi Analysis of Growth and Viability in Drosophila Cells.”. Science, 303, 5659, Pp. 832-5. doi:10.1126/science.1091266
Michael Boutros, Amy Kiger, Susan Armknecht, Kim Kerr, Marc Hild, Britta Koch, Stefan Haas, Renato Paro, Norbert Perrimon, and Heidelberg Fly Array Consortium. 2004. “Genome-Wide RNAi Analysis of Growth and Viability in Drosophila Cells.”. Science, 303, 5659, Pp. 832-5. doi:10.1126/science.1091266