If the goal is human disease-related studies, why do functional genomics in Drosophila?
- a simple, low-redundancy, well-annotated genome
- all major signaling pathways conserved (Hh, Toll, Hippo, etc.)
- best understood model of insect vectors of diseases (e.g. mosquitoes) and insect pests
- proven model of human diseases including cancer, heart disease, obesity and diabetes, neurodegenerative diseases, congenital disorders, kidney stones, neuronal injury, behavioral disorders, and more
Many researchers use our technologies to to uncover new findings relevant to disease and potential drug targets. We welcome inquiries from non-Drosophila researchers looking to connect with specific expertise and resources. We also recommend our fly models of human diseases blog.
See links below to relevant online tools, reagents, publications, and more.