Genome-wide screen
Content tagged with Genome-wide screen
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Event
We've submitted abstracts and plan to participate in the Entomological Society of America's Entomology 2024 conference in Phoneix, AZ, this fall to connect with new audiences as we continue development of our CRISPR screening platform for screens in...
Virtual CRISPR Workshop 'at' ADRC 2023
Event
The DRSC is collaborating with other groups to present a virtual workshop on CRISPR technologies for Drosophila cells and in vivo as part of the GSA Annual Drosophila Research Conference 2023.
DRSC & DRTC Genetics and Genomics Workshop
Event
The DRSC is collaborating with the Drosophila Research and Training Center of Nigeria and the laboratory of Prof. Ross Cagan (University of Glasgow) to present an online workshop on Drosophila genomics and genetics.
So you want to do a CRISPR pooled screen in insect cells? You can! Here's how
News
At the DRSC-BTRR, we've been doing a lot of pooled-format CRISPR knockout screens in Drosophila cells. We're finding the results to be robust and reproducible. And best of all, the results have been informative, providing insights into diverse areas of...
DRSC/TRiP and DRSC-BTRR Office Hours
News
New this fall: Online office hours! Do you have questions about modifying Drosophila cell lines with CRISPR or performing large-scale cell screens? Questions about in vivo RNAi with TRiP fly stocks or CRISPR knockout or activation with our sgRNA fly...
DRSC-Biomedical Technology Research Resource
News
We are pleased to announce that we have been funded by NIH NIGMS to form the Drosophila Research & Screening Center-Biomedical Technology Research Resource (DRSC-BTRR). The P41-funded DRSC-BTRR (N. Perrimon, PI; S. Mohr, Co-I) builds upon and extends past...
Cell-based RNAi screening helps reveal host-microbe interactions--two new screen reports
News
Laboratories at the Skirball Institute at New York University and the Boyce Thompson Institute at Cornell University reported results of two different cell-based Drosophila RNAi screens in papers published this week. The screens have in common that they...
Missed us at ADRC 2018? View our workshop slides!
News
Thank you to all those who attended our workshop at last week's Annual Drosophila Research Conference in Philadelphia, PA, USA. It was great to talk fly stocks, cell screens, and bioinformatics with the community. We are here to help and look forward to...
Pooled-format CRISPR screens in Drosophila cells
News
The DRSC/TRiP-FGR is pleased to support collaborations on pooled CRISPR screens using the method recently, reported in eLife by Viswanatha et al. (PDF download file below). From the abstract: "... Here, we developed a site-specific integration strategy...
DRSC at 17th annual World Preclinical Congress
Event
The DRSC/TRiP-FGR Director, Stephanie Mohr, will be co-teaching a short course on cell-based screening and single-cell studies, as well as co-moderating a discussion session, at the 17th annual World Preclinical Congress.
Bibliographic References tagged with Genome-wide screen
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Fillip Port, George Hausmann, and Konrad Basler. 2011. “A Genome-Wide RNA Interference Screen Uncovers Two P24 Proteins As Regulators of Wingless Secretion.”. EMBO Rep, 12, 11, Pp. 1144-52. doi:10.1038/embor.2011.165
Fillip Port, George Hausmann, and Konrad Basler. 2011. “A Genome-Wide RNA Interference Screen Uncovers Two P24 Proteins As Regulators of Wingless Secretion.”. EMBO Rep, 12, 11, Pp. 1144-52. doi:10.1038/embor.2011.165
Adam Friedman and Norbert Perrimon. 2006. “A Functional RNAi Screen for Regulators of Receptor Tyrosine Kinase and ERK Signalling.”. Nature, 444, 7116, Pp. 230-4. doi:10.1038/nature05280
Adam Friedman and Norbert Perrimon. 2006. “A Functional RNAi Screen for Regulators of Receptor Tyrosine Kinase and ERK Signalling.”. Nature, 444, 7116, Pp. 230-4. doi:10.1038/nature05280
Jennifer Rohn, David Sims, Tao Liu, Marina Fedorova, Frieder Schöck, Joseph Dopie, Maria Vartiainen, Amy Kiger, Norbert Perrimon, and Buzz Baum. 2011. “Comparative RNAi Screening Identifies a Conserved Core Metazoan Actinome by Phenotype.”. J Cell Biol, 194, 5, Pp. 789-805. doi:10.1083/jcb.201103168
Jennifer Rohn, David Sims, Tao Liu, Marina Fedorova, Frieder Schöck, Joseph Dopie, Maria Vartiainen, Amy Kiger, Norbert Perrimon, and Buzz Baum. 2011. “Comparative RNAi Screening Identifies a Conserved Core Metazoan Actinome by Phenotype.”. J Cell Biol, 194, 5, Pp. 789-805. doi:10.1083/jcb.201103168
Norbert Perrimon and Bernard Mathey-Prevot. 2007. “Applications of High-Throughput RNA Interference Screens to Problems in Cell and Developmental Biology.”. Genetics, 175, 1, Pp. 7-16. doi:10.1534/genetics.106.069963
Norbert Perrimon and Bernard Mathey-Prevot. 2007. “Applications of High-Throughput RNA Interference Screens to Problems in Cell and Developmental Biology.”. Genetics, 175, 1, Pp. 7-16. doi:10.1534/genetics.106.069963
Yousang Gwack, Sonal Srikanth, Stefan Feske, Fernando Cruz-Guilloty, Masatsugu Oh-hora, Daniel Neems, Patrick Hogan, and Anjana Rao. 2007. “Biochemical and Functional Characterization of Orai Proteins.”. J Biol Chem, 282, 22, Pp. 16232-43. doi:10.1074/jbc.M609630200
Yousang Gwack, Sonal Srikanth, Stefan Feske, Fernando Cruz-Guilloty, Masatsugu Oh-hora, Daniel Neems, Patrick Hogan, and Anjana Rao. 2007. “Biochemical and Functional Characterization of Orai Proteins.”. J Biol Chem, 282, 22, Pp. 16232-43. doi:10.1074/jbc.M609630200
Stephanie Mohr and Norbert Perrimon. 2012. “RNAi Screening: New Approaches, Understandings, and Organisms.”. Wiley Interdiscip Rev RNA, 3, 2, Pp. 145-58. doi:10.1002/wrna.110
Stephanie Mohr and Norbert Perrimon. 2012. “RNAi Screening: New Approaches, Understandings, and Organisms.”. Wiley Interdiscip Rev RNA, 3, 2, Pp. 145-58. doi:10.1002/wrna.110
Jianrong Lu, Marie-Laure Ruhf, Norbert Perrimon, and Philip Leder. 2007. “A Genome-Wide RNA Interference Screen Identifies Putative Chromatin Regulators Essential for E2F Repression.”. Proc Natl Acad Sci U S A, 104, 22, Pp. 9381-6. doi:10.1073/pnas.0610279104
Jianrong Lu, Marie-Laure Ruhf, Norbert Perrimon, and Philip Leder. 2007. “A Genome-Wide RNA Interference Screen Identifies Putative Chromatin Regulators Essential for E2F Repression.”. Proc Natl Acad Sci U S A, 104, 22, Pp. 9381-6. doi:10.1073/pnas.0610279104
Adam Friedman, George Tucker, Rohit Singh, Dong Yan, Arunachalam Vinayagam, Yanhui Hu, Richard Binari, Pengyu Hong, Xiaoyun Sun, Maura Porto, Svetlana Pacifico, Thilakam Murali, Russell Finley, John Asara, Bonnie Berger, and Norbert Perrimon. 2011. “Proteomic and Functional Genomic Landscape of Receptor Tyrosine Kinase and Ras to Extracellular Signal-Regulated Kinase Signaling.”. Sci Signal, 4, 196, Pp. rs10. doi:10.1126/scisignal.2002029
Adam Friedman, George Tucker, Rohit Singh, Dong Yan, Arunachalam Vinayagam, Yanhui Hu, Richard Binari, Pengyu Hong, Xiaoyun Sun, Maura Porto, Svetlana Pacifico, Thilakam Murali, Russell Finley, John Asara, Bonnie Berger, and Norbert Perrimon. 2011. “Proteomic and Functional Genomic Landscape of Receptor Tyrosine Kinase and Ras to Extracellular Signal-Regulated Kinase Signaling.”. Sci Signal, 4, 196, Pp. rs10. doi:10.1126/scisignal.2002029
Lan Xu, Xiaohao Yao, Xiaochu Chen, Peiyuan Lu, Biliang Zhang, and Tony Ip. 2007. “Msk Is Required for Nuclear Import of TGF-{beta} BMP-Activated Smads.”. J Cell Biol, 178, 6, Pp. 981-94. doi:10.1083/jcb.200703106
Lan Xu, Xiaohao Yao, Xiaochu Chen, Peiyuan Lu, Biliang Zhang, and Tony Ip. 2007. “Msk Is Required for Nuclear Import of TGF-{beta} BMP-Activated Smads.”. J Cell Biol, 178, 6, Pp. 981-94. doi:10.1083/jcb.200703106
Reid Aikin, Alexandra Cervantes, Gisela D’Angelo, Laurent Ruel, Sandra Lacas-Gervais, Sébastien Schaub, and Pascal Thérond. 2012. “A Genome-Wide RNAi Screen Identifies Regulators of Cholesterol-Modified Hedgehog Secretion in Drosophila.”. PLoS One, 7, 3, Pp. e33665. doi:10.1371/journal.pone.0033665
Reid Aikin, Alexandra Cervantes, Gisela D’Angelo, Laurent Ruel, Sandra Lacas-Gervais, Sébastien Schaub, and Pascal Thérond. 2012. “A Genome-Wide RNAi Screen Identifies Regulators of Cholesterol-Modified Hedgehog Secretion in Drosophila.”. PLoS One, 7, 3, Pp. e33665. doi:10.1371/journal.pone.0033665