Screening technologies
Content tagged with Screening technologies
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Event
We've submitted abstracts and plan to participate in the Entomological Society of America's Entomology 2024 conference in Phoneix, AZ, this fall to connect with new audiences as we continue development of our CRISPR screening platform for screens in...
New cell lines & new understandings using cutting-edge techniques
News
As a facility that supports large-scale screens in Drosophila and other insect cell lines, we get excited about reports of new Drosophila cell lines and related info. We'd like to highlight two recent papers. One report, a collaboration between Amanda...
DRSC/TRiP and DRSC-BTRR Office Hours
News
New this fall: Online office hours! Do you have questions about modifying Drosophila cell lines with CRISPR or performing large-scale cell screens? Questions about in vivo RNAi with TRiP fly stocks or CRISPR knockout or activation with our sgRNA fly...
DRSC-BTRR at the GSA Molecular Parasitology Meeting XXXI
Event
The Drosophila Research & Screening Center-Biomedical Technology Research Resource (DRSC-BTRR) will be represented at the GSA's Molecular Parasitology Meeting XXXI (a virtual event). Look for a presentation by Viswanatha et al. on our work establishing...
Drosophila cell screen with DRSC reagent library contributes to identification of new therapeutic target for renal cancer
News
We here at the DRSC/TRiP are thrilled to see this study from Hilary Nicholson et al. published in Science Signaling. The study provides a great example of how screens in Drosophila cultured cells can be used as part of a cross-species platform aimed at...
Micropublication relevant to TRiP fly stocks
News
Users of TRiP RNAi and sgRNA fly stocks take note: the Weake lab at Purdue University brought to our attention that some TRiP fly stocks carry a mutant allele of seveneless. Jonathan Zirin worked with Spencer Escobedo and Vikki Weake, as well as with...
DRSC&TRiP at ASCB|EMBO 2018
Event
The DRSC & TRiP will be represented at the ASCB|EMBO 2018 conference in the form of a poster that includes information about our collaboration with O. Kanca in the H. Bellen lab at Baylor College of Medicine to tag Drosophila S2R+ cell lines with GFP...
Director S. Mohr presents at the Countway Longwood Author Series
Event
On June 18th, DRSC/TRiP-FGR Director Dr. Stephanie Mohr will present an introduction to Drosophila research and discuss her book First in Fly: Drosophila Research and Biological Discussion, as part of the Countway Longwood Author Series. The event will be...
DRSC & TRiP Workshop at ADRC
Event
The DRSC & TRiP will be hosting a workshop at the Annual Drosophila Research Conference in Philadelphia, PA. The workshop is scheduled for Friday, April 13th from 1:45 to 3:45 PM. Come hear from DRSC & TRiP leaders Norbert Perrimon, Jonathan Zirin...
Bibliographic References tagged with Screening technologies
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Ying Xu, Raghuvir Viswanatha, Oleg Sitsel, Daniel Roderer, Haifang Zhao, Christopher Ashwood, Cecilia Voelcker, Songhai Tian, Stefan Raunser, Norbert Perrimon, and Min Dong. 2022. “CRISPR Screens in Drosophila Cells Identify Vsg As a Tc Toxin Receptor”. Nature, 610, 7931, Pp. 349-55. doi:10.1038/s41586-022-05250-7
Ying Xu, Raghuvir Viswanatha, Oleg Sitsel, Daniel Roderer, Haifang Zhao, Christopher Ashwood, Cecilia Voelcker, Songhai Tian, Stefan Raunser, Norbert Perrimon, and Min Dong. 2022. “CRISPR Screens in Drosophila Cells Identify Vsg As a Tc Toxin Receptor”. Nature, 610, 7931, Pp. 349-55. doi:10.1038/s41586-022-05250-7
Hans M. Dalton, Raghuvir Viswanatha, Ricky Brathwaite Jr., Jae Sophia Zuno, Stephanie Mohr, Norbert Perrimon, and Clement Y. Chow. 2021. “A Genome-Wide CRISPR Screen Identifies the Glycosylation Enzyme DPM1 As a Modifier of DPAGT1 Deficiency and ER Stress”. BioRxiv
Hans M. Dalton, Raghuvir Viswanatha, Ricky Brathwaite Jr., Jae Sophia Zuno, Stephanie Mohr, Norbert Perrimon, and Clement Y. Chow. 2021. “A Genome-Wide CRISPR Screen Identifies the Glycosylation Enzyme DPM1 As a Modifier of DPAGT1 Deficiency and ER Stress”. BioRxiv
Xiangzhao Yue, Yongkang Liang, Zhishuang Wei, Jun Lv, Yongjin Cai, Xiaobin Fan, Wenqing Zhang, and Jie Chen. 2021. “Genome-Wide in Vitro and in Vivo RNAi Screens Reveal Fer3 to Be an Important Regulator of Kkv Transcription in Drosophila”. Insect Sci. doi:10.1111/1744-7917.12954
Xiangzhao Yue, Yongkang Liang, Zhishuang Wei, Jun Lv, Yongjin Cai, Xiaobin Fan, Wenqing Zhang, and Jie Chen. 2021. “Genome-Wide in Vitro and in Vivo RNAi Screens Reveal Fer3 to Be an Important Regulator of Kkv Transcription in Drosophila”. Insect Sci. doi:10.1111/1744-7917.12954
Raghuvir Viswanatha, Roderick Brathwaite, Yanhui Hu, Zhongchi Li, Jonathan Rodiger, Pierre Merckaert, Verena Chung, Stephanie Mohr, and Norbert Perrimon. 2019. “Pooled CRISPR Screens in Drosophila Cells”. Curr Protoc Mol Biol, 129, 1, Pp. e111. doi:10.1002/cpmb.111
Raghuvir Viswanatha, Roderick Brathwaite, Yanhui Hu, Zhongchi Li, Jonathan Rodiger, Pierre Merckaert, Verena Chung, Stephanie Mohr, and Norbert Perrimon. 2019. “Pooled CRISPR Screens in Drosophila Cells”. Curr Protoc Mol Biol, 129, 1, Pp. e111. doi:10.1002/cpmb.111
Hilary Nicholson, Zeshan Tariq, Benjamin Housden, Rebecca Jennings, Laura Stransky, Norbert Perrimon, Sabina Signoretti, and William Kaelin. 2019. “HIF-Independent Synthetic Lethality Between CDK4 6 Inhibition and VHL Loss across Species”. Sci Signal, 12, 601. doi:10.1126/scisignal.aay0482
Hilary Nicholson, Zeshan Tariq, Benjamin Housden, Rebecca Jennings, Laura Stransky, Norbert Perrimon, Sabina Signoretti, and William Kaelin. 2019. “HIF-Independent Synthetic Lethality Between CDK4 6 Inhibition and VHL Loss across Species”. Sci Signal, 12, 601. doi:10.1126/scisignal.aay0482
Stephanie Mohr, Kirstin Rudd, Yanhui Hu, Wei Song, Quentin Gilly, Michael Buckner, Benjamin Housden, Colleen Kelley, Jonathan Zirin, Rong Tao, Gabriel Amador, Katarzyna Sierzputowska, Aram Comjean, and Norbert Perrimon. 2017. “Zinc Detoxification: A Functional Genomics and Transcriptomics Analysis in Drosophila Melanogaster Cultured Cells”. G3 (Bethesda). doi:10.1534/g3.117.300447
Stephanie Mohr, Kirstin Rudd, Yanhui Hu, Wei Song, Quentin Gilly, Michael Buckner, Benjamin Housden, Colleen Kelley, Jonathan Zirin, Rong Tao, Gabriel Amador, Katarzyna Sierzputowska, Aram Comjean, and Norbert Perrimon. 2017. “Zinc Detoxification: A Functional Genomics and Transcriptomics Analysis in Drosophila Melanogaster Cultured Cells”. G3 (Bethesda). doi:10.1534/g3.117.300447
Eui Jae Sung, Masasuke Ryuda, Hitoshi Matsumoto, Outa Uryu, Masanori Ochiai, Molly Cook, Na Young Yi, Huanchen Wang, James Putney, Gary Bird, Stephen Shears, and Yoichi Hayakawa. 2017. “Cytokine Signaling through Drosophila Mthl10 Ties Lifespan to Environmental Stress”. Proc Natl Acad Sci U S A. doi:10.1073/pnas.1712453115
Eui Jae Sung, Masasuke Ryuda, Hitoshi Matsumoto, Outa Uryu, Masanori Ochiai, Molly Cook, Na Young Yi, Huanchen Wang, James Putney, Gary Bird, Stephen Shears, and Yoichi Hayakawa. 2017. “Cytokine Signaling through Drosophila Mthl10 Ties Lifespan to Environmental Stress”. Proc Natl Acad Sci U S A. doi:10.1073/pnas.1712453115
Zanet, Benrabah, Li, Pélissier-Monier, Chanut-Delalande, Ronsin, Bellen, Payre, and Plaza. 2015. “Pri SORF Peptides Induce Selective Proteasome-Mediated Protein Processing”. Science, 349, 6254, Pp. 1356-8. doi:10.1126/science.aac5677
Zanet, Benrabah, Li, Pélissier-Monier, Chanut-Delalande, Ronsin, Bellen, Payre, and Plaza. 2015. “Pri SORF Peptides Induce Selective Proteasome-Mediated Protein Processing”. Science, 349, 6254, Pp. 1356-8. doi:10.1126/science.aac5677
Chen X and Xu L. 2016. “Genome-Wide RNAi Screening to Dissect the TGF-β Signal Transduction Pathway”. Methods in Molecular Biology
Chen X and Xu L. 2016. “Genome-Wide RNAi Screening to Dissect the TGF-β Signal Transduction Pathway”. Methods in Molecular Biology
Benjamin Housden, Matthias Muhar, Matthew Gemberling, Charles Gersbach, Didier YR Stainier, Geraldine Seydoux, Stephanie Mohr, Johannes Zuber, and Norbert Perrimon. 2016. “Loss-of-Function Genetic Tools for Animal Models: Cross-Species and Cross-Platform Differences”. Nat Rev Genet
Benjamin Housden, Matthias Muhar, Matthew Gemberling, Charles Gersbach, Didier YR Stainier, Geraldine Seydoux, Stephanie Mohr, Johannes Zuber, and Norbert Perrimon. 2016. “Loss-of-Function Genetic Tools for Animal Models: Cross-Species and Cross-Platform Differences”. Nat Rev Genet