Micropublication relevant to TRiP fly stocks

April 9, 2019
Figure 1 from the Escobedo et al. micropublication

Users of TRiP RNAi and sgRNA fly stocks take note: the Weake lab at Purdue University brought to our attention that some TRiP fly stocks carry a mutant allele of seveneless. Jonathan Zirin worked with Spencer Escobedo and Vikki Weake, as well as with folks at the Bloomington Drosophila Stock Center, to quickly identify the source, sequence the mutant allele, and pubilsh a micropublication so we can get the details to the community. Bottom line, as stated in the micropublication, "The presence of the sev[21]  mutation will not generally affect the use of these stocks, as the X chromosome is typically segregated out or heterozygous during experiments.​" We encourage you to read the micropublication to get the details. Citation details: Escobedo, SE; Zirin, J; Weake, VM (2019). TRiP stocks contain a previously uncharacterized loss-of-function sevenless allele. microPublication Biology. 10.17912/micropub.biology.000097