Off-target analysis

Content tagged with Off-target analysis

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New publications from the DRSC bioinformatics team

News
The DRSC bioinformatics team, led by Dr. Claire Yanhui Hu, has recently published two new papers. One reports development of BioLitMine, an advanced literature mining resource. The other provides an overview of our online resources, which can be grouped...

DRSC & TRiP Workshop at ADRC

Event
The DRSC & TRiP will be hosting a workshop at the Annual Drosophila Research Conference in Philadelphia, PA. The workshop is scheduled for Friday, April 13th from 1:45 to 3:45 PM. Come hear from DRSC & TRiP leaders Norbert Perrimon, Jonathan Zirin...

Now Available: Our 2017 NAR database issue update

News
Read about the DRSC/TRiP Functional Genomics Resources online tools and more in our 2017 Nucleic Acids Research database issue update publication. Tables 1 & 2 in particular are meant to give you a quick look at what online tools we offer and how they fit...

Bibliographic References tagged with Off-target analysis

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Yanhui Hu, Aram Comjean, Jonathan Rodiger, Yifang Liu, Yue Gao, Verena Chung, Jonathan Zirin, Norbert Perrimon, and Stephanie Mohr. 2020. “FlyRNAi.Org-the Database of the Drosophila RNAi Screening Center and Transgenic RNAi Project: 2021 Update”. Nucleic Acids Res. doi:10.1093/nar/gkaa936
Yanhui Hu, Aram Comjean, Jonathan Rodiger, Yifang Liu, Yue Gao, Verena Chung, Jonathan Zirin, Norbert Perrimon, and Stephanie Mohr. 2020. “FlyRNAi.Org-the Database of the Drosophila RNAi Screening Center and Transgenic RNAi Project: 2021 Update”. Nucleic Acids Res. doi:10.1093/nar/gkaa936
Raghuvir Viswanatha, Roderick Brathwaite, Yanhui Hu, Zhongchi Li, Jonathan Rodiger, Pierre Merckaert, Verena Chung, Stephanie Mohr, and Norbert Perrimon. 2019. “Pooled CRISPR Screens in Drosophila Cells”. Curr Protoc Mol Biol, 129, 1, Pp. e111. doi:10.1002/cpmb.111
Raghuvir Viswanatha, Roderick Brathwaite, Yanhui Hu, Zhongchi Li, Jonathan Rodiger, Pierre Merckaert, Verena Chung, Stephanie Mohr, and Norbert Perrimon. 2019. “Pooled CRISPR Screens in Drosophila Cells”. Curr Protoc Mol Biol, 129, 1, Pp. e111. doi:10.1002/cpmb.111
Stephanie Mohr, Kirstin Rudd, Yanhui Hu, Wei Song, Quentin Gilly, Michael Buckner, Benjamin Housden, Colleen Kelley, Jonathan Zirin, Rong Tao, Gabriel Amador, Katarzyna Sierzputowska, Aram Comjean, and Norbert Perrimon. 2017. “Zinc Detoxification: A Functional Genomics and Transcriptomics Analysis in Drosophila Melanogaster Cultured Cells”. G3 (Bethesda). doi:10.1534/g3.117.300447
Stephanie Mohr, Kirstin Rudd, Yanhui Hu, Wei Song, Quentin Gilly, Michael Buckner, Benjamin Housden, Colleen Kelley, Jonathan Zirin, Rong Tao, Gabriel Amador, Katarzyna Sierzputowska, Aram Comjean, and Norbert Perrimon. 2017. “Zinc Detoxification: A Functional Genomics and Transcriptomics Analysis in Drosophila Melanogaster Cultured Cells”. G3 (Bethesda). doi:10.1534/g3.117.300447
Chen X and Xu L. 2016. “Genome-Wide RNAi Screening to Dissect the TGF-β Signal Transduction Pathway”. Methods in Molecular Biology
Chen X and Xu L. 2016. “Genome-Wide RNAi Screening to Dissect the TGF-β Signal Transduction Pathway”. Methods in Molecular Biology
Benjamin Housden, Matthias Muhar, Matthew Gemberling, Charles Gersbach, Didier YR Stainier, Geraldine Seydoux, Stephanie Mohr, Johannes Zuber, and Norbert Perrimon. 2016. “Loss-of-Function Genetic Tools for Animal Models: Cross-Species and Cross-Platform Differences”. Nat Rev Genet
Benjamin Housden, Matthias Muhar, Matthew Gemberling, Charles Gersbach, Didier YR Stainier, Geraldine Seydoux, Stephanie Mohr, Johannes Zuber, and Norbert Perrimon. 2016. “Loss-of-Function Genetic Tools for Animal Models: Cross-Species and Cross-Platform Differences”. Nat Rev Genet
2015. “DRSC: RNA Binding Protein Library S2R+ Baseline Data (data Support Page for Mohr et Al. 2015 ‘Reagent and Data Resources for Investigation of RNA Binding Protein Functions in Drosophila Melanogaster Cultured Cells’ in G3)”
2015. “DRSC: RNA Binding Protein Library S2R+ Baseline Data (data Support Page for Mohr et Al. 2015 ‘Reagent and Data Resources for Investigation of RNA Binding Protein Functions in Drosophila Melanogaster Cultured Cells’ in G3)”
Christophe Echeverri and Norbert Perrimon. 2006. “High-Throughput RNAi Screening in Cultured Cells: A User’s Guide.”. Nat Rev Genet, 7, 5, Pp. 373-84. doi:10.1038/nrg1836
Christophe Echeverri and Norbert Perrimon. 2006. “High-Throughput RNAi Screening in Cultured Cells: A User’s Guide.”. Nat Rev Genet, 7, 5, Pp. 373-84. doi:10.1038/nrg1836
Meghana Kulkarni, Matthew Booker, Serena Silver, Adam Friedman, Pengyu Hong, Norbert Perrimon, and Bernard Mathey-Prevot. 2006. “Evidence of Off-Target Effects Associated With Long DsRNAs in Drosophila Melanogaster Cell-Based Assays.”. Nat Methods, 3, 10, Pp. 833-8. doi:10.1038/nmeth935
Meghana Kulkarni, Matthew Booker, Serena Silver, Adam Friedman, Pengyu Hong, Norbert Perrimon, and Bernard Mathey-Prevot. 2006. “Evidence of Off-Target Effects Associated With Long DsRNAs in Drosophila Melanogaster Cell-Based Assays.”. Nat Methods, 3, 10, Pp. 833-8. doi:10.1038/nmeth935
Nadire Ramadan, Ian Flockhart, Matthew Booker, Norbert Perrimon, and Bernard Mathey-Prevot. 2007. “Design and Implementation of High-Throughput RNAi Screens in Cultured Drosophila Cells.”. Nat Protoc, 2, 9, Pp. 2245-64. doi:10.1038/nprot.2007.250
Nadire Ramadan, Ian Flockhart, Matthew Booker, Norbert Perrimon, and Bernard Mathey-Prevot. 2007. “Design and Implementation of High-Throughput RNAi Screens in Cultured Drosophila Cells.”. Nat Protoc, 2, 9, Pp. 2245-64. doi:10.1038/nprot.2007.250
Stephanie Mohr, Chris Bakal, and Norbert Perrimon. 2010. “Genomic Screening With RNAi: Results and Challenges.”. Annu Rev Biochem, 79, Pp. 37-64. doi:10.1146/annurev-biochem-060408-092949
Stephanie Mohr, Chris Bakal, and Norbert Perrimon. 2010. “Genomic Screening With RNAi: Results and Challenges.”. Annu Rev Biochem, 79, Pp. 37-64. doi:10.1146/annurev-biochem-060408-092949