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Wilinski and colleagues release "FlyScape" for metabolic network visualization

News

The DRSC congratulates Wilinski et al. at the University of Michigan for their release and publication of FlyScape, a tool for metabolic network visualization. Rapid metabolic shifts occur during the transition between hunger and satiety in Drosophila...

FlyRNAi.org-the database of the Drosophila RNAi screening center and transgenic RNAi project: 2021 update

Journal Article

The FlyRNAi database at the Drosophila RNAi Screening Center and Transgenic RNAi Project (DRSC/TRiP) provides a suite of online resources that facilitate functional genomics studies with a special emphasis on Drosophila melanogaster. Currently, the...

InsulinNetwork

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InsulinNet provides access to a comprehensive Drosophila InR/PI3K/Akt network generated at the Perrimon Lab and DRSC, as described in Vinayagam et al. 2016. Cell Reports (see below). The data set, query, and visualization provide access to information...

Protein complex-based analysis framework for high-throughput data sets.

Journal Article

Analysis of high-throughput data increasingly relies on pathway annotation and functional information derived from Gene Ontology. This approach has limitations, in particular for the analysis of network dynamics over time or under different experimental...

Molecular Interaction Search Tool (MIST): an integrated resource for mining gene and protein interaction data

Journal Article

Model organism and human databases are rich with information about genetic and physical interactions. These data can be used to interpret and guide the analysis of results from new studies and develop new hypotheses. Here, we report the development of the...

COMPLEAT Documentation

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URL http://www.flyrnai.org/compleat/ Data upload page Species: The user may choose human, fly or yeast Data files: The user may upload multiple datasets in one file or multiple files. Tab-separated text files, and excel files (.xls, .xlsx, .xlsm) will be...

COMPLEAT

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COMPLEAT (protein COMPLex Enrichment Analysis Tool) is an online tool used to analyze high-throughput datasets (or small-scale datasets) using protein complex enrichment analysis. The tool uses a protein complex resource as the backend annotation data...

SignedPPI Documentation

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URL http://www.flyrnai.org/SignedPPI/ Input Form Enter gene and/or protein identifiers to the text area or upload a file with gene/protein identifiers. Accepted gene/protein identifiers: FBgn, CG, symbol, UniProt, Entrez Gene Id. Format of data file(s)...

DGET

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The Drosophila Gene Expression Tool (DGET) lets you enter one or a list of genes, then view and analyze modENCODE and other expression data for those genes. You can view results as a heat map, bar graph, or network visualization. Analyses include...

Nucleolar image-based screen dataset viewable online with OMERO

News

The DRSC has worked with the HMS Image Data Management Core to make a ~3 TB image fluorescence confocal screen image dataset from the screen reported in Neumuller et al. available online. And not just available--with several interaction options! At the...

New publications from the DRSC bioinformatics team

News

The DRSC bioinformatics team, led by Dr. Claire Yanhui Hu, has recently published two new papers. One reports development of BioLitMine, an advanced literature mining resource. The other provides an overview of our online resources, which can be grouped...

DGET Documentation

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URL http://www.flyrnai.org/tools/dget/web DGET- Drosophila Gene Expression Tool DGET Overview DGET was designed to facilitate the retrieval and analysis of RNA-Seq based expression data in a high-throughput fashion. The tool can be compared with...