The TRiP is excited to announce our new TRiP-CRISPR transgenic fly libraries for gene knockout and overexpression. Visit the sgRNA tracking site to download and search existing TRiP-CRISPR fly stocks by gene or stock ID to obtain information on sgRNA sequence, function, vector, injection site, and availablility.
Those of us lucky enough to be at the Annual Drosophila Research Conference this morning saw a great talk by Francois Payre about regulation of Shavenbaby by small ORFs. A genome-wide cell-based screen done at the DRSC by Emilie Benrabah identified the mechanism of regulation. As this exemplifies, cell screens can help identify key pathways and factors that can then be followed up with in vivo studies.
The DRSC/TRiP-FGR is pleased to announce that we recently updated our high-throughput, high-content imaging system. Through funds from NIH, HHMI, and the Harvard Medical School Tools & Technology program, we were able to get a
We have updated our CRISPR sgRNA design tool. The results and JBrowse display are now based on Drosophila melanogasterFlyBase genome assembly release 6. We have also added seed scores in addition to efficiency prediction scores and other values available on detailed views of sgRNA designs. Quick tips: start a search with a gene symbol or other identifier, use the
The DRSC & TRiP leadership consider the Annual Drosophila Research Conference the 'must-go' conference of the year. We use ADRC meetings as an opportunity to update the community on existing and new services, reagent collections, and online tools, as well as for one-on-one consults with researchers planning high-throughput screens. The next ADRC is scheduled for April 11-15. 2018, in Philadelphia, PA, USA. Feel free to contact us if you'll also be there and would Read more about 59th Annual Drosophila Research Conference
The DRSC leadership will be participating in the Genomics Discovery Initiative annual meeting 2017, which is hosted by GE Healthcare Dharmacon. We look forward to conneting with and learning from colleagues in academia and industry represented at the meeting. Events on Friday, Oct. 13, 2017, are open to the public.
On Sept. 27, 2017, DRSC/TRiP-FGR Director S. Mohr will present a talk on "High-throughput CRISPR-based approaches to cancer target identification" at the 2017 CHI Discovery on Target conference at the Westin Copley Place, Boston, MA, USA.
The DRSC & TRiP will be at the Annual Drosophila Research Conference (aka 'the fly meeting') in San Diego, CA, in March/April of 2017. Please feel free to contact us if you'd like to set up a meeting to discuss a screen project or other research need we can help with.