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Screenshot of a 2015 Science paper from Payre and colleagues

Francois Payre's plenary talk at ADRC 2017 features results from DRSC cell-based screen

March 30, 2017

Those of us lucky enough to be at the Annual Drosophila Research Conference this morning saw a great talk by Francois Payre about regulation of Shavenbaby by small ORFs. A genome-wide cell-based screen done at the DRSC by Emilie Benrabah identified the mechanism of regulation. As this exemplifies, cell screens can help identify key pathways and factors that can then be followed up with in vivo studies.

New stocks added to the TRiP in vivo RNAi library

January 6, 2017

The TRiP has updated and curated our list of in vivo RNAi reagents for gene knockdown in fruitflies. To date, we have produced over 13,000 stocks for the benefit of the scientific community.

Visit the in vivo RNAi fly stocks and vectors page to download an excel file with the full list of fly stocks now available for order from the Bloomington Drosophila Stock Center (BDSC) and the

Read more about New stocks added to the TRiP in vivo RNAi library

CRISPR sgRNA design tool now based on Drosophila genome assembly 6

December 21, 2016

We have updated our CRISPR sgRNA design tool. The results and JBrowse display are now based on Drosophila melanogaster FlyBase genome assembly release 6. We have also added seed scores in addition to efficiency prediction scores and other values available on detailed views of sgRNA designs. Quick tips: start a search with a gene symbol or other identifier, use the

Read more about CRISPR sgRNA design tool now based on Drosophila genome assembly 6
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Events

2018 Apr 11

59th Annual Drosophila Research Conference

Apr 11 (All day) to Apr 15 (All day)

Location: 

Philadelphia, PA, USA
The DRSC & TRiP leadership consider the Annual Drosophila Research Conference the 'must-go' conference of the year. We use ADRC meetings as an opportunity to update the community on existing and new services, reagent collections, and online tools, as well as for one-on-one consults with researchers planning high-throughput screens. The next ADRC is scheduled for April 11-15. 2018, in Philadelphia, PA, USA. Feel free to contact us if you'll also be there and would Read more about 59th Annual Drosophila Research Conference
2017 Oct 12

DRSC attendance at the Genomics Discovery Initiative Annual Meeting 2017

(All day)

Location: 

Philadelphia, PA
The DRSC leadership will be participating in the Genomics Discovery Initiative annual meeting 2017, which is hosted by GE Healthcare Dharmacon. We look forward to conneting with and learning from colleagues in academia and industry represented at the meeting. Events on Friday, Oct. 13, 2017, are open to the public.
2017 Sep 25

Presentation on "High-throughput CRISPR-based approaches to cancer target identification" at CHI Discovery on Target in Boston, MA

Sep 25 (All day) to Sep 29 (All day)

Location: 

Boston, MA, USA

On Sept. 27, 2017, DRSC/TRiP-FGR Director S. Mohr will present a talk on "High-throughput CRISPR-based approaches to cancer target identification" at the 2017 CHI Discovery on Target conference at the Westin Copley Place, Boston, MA, USA.

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2017 May 10

Presentation at Genome Editing and Trangenic Congress USA

10:00am

Location: 

Boston, MA

Stephanie will be presenting at the Genome Editing and Transgenic Congress USA in Boston, MA, on May 10, 2017 (time TBD). She plans to cover the following topics.

  • Strategy and results of optimization of Cas9 fusion proteins for CRISPR activation in cells and in vivo
  • Genome-scale design of single guide RNAs (sgRNAs) for CRISPR activation
  • Use of CRISPR activation in Drosophila for large-scale gene function discovery and disease modeling
2017 Mar 29

DRSC & TRiP at the fly meeting

Mar 29 (All day) to Apr 02 (All day)

Location: 

San Diego, CA

The DRSC and TRiP are represented at the fly meeting! Stop by posters 712A and 709A to learn about new technologies and online resources. Photos of the posters are welcome!

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