The DRSC bioinformatics team, led by Dr. Claire Yanhui Hu, has recently published two new papers.
One reports development of BioLitMine, an advanced literature mining resource. The other provides an overview of our online resources, which can be grouped into reagent, gene, and data-focused resources.
Did you miss the presentations from Claire Hu and Jonathan Zirin at the June 2020 Boston Area Drosophila Meeting? No problem! The slides can be accessed from this post. Click the title above to view the whole post, then scroll down to access the PDFs. These presentations describe what's new and next in bioinformatics and in vivo technologies at the DRSC/TRiP. Feel free to reach out with questions. Interested in the BAD meeting? Info about the meeting can be found here. Read more about DRSC/TRiP presentations from June 2020 Boston Area Drosophila Meeting
Paralogs can be defined as related genes within a genome that are thought to arise from gene duplication events. Because paralogous proteins share amino acid identity, they can have redundant functions. But the picture is not necessarily so straightforward. Indeed, there are examples in which paralogous genes have distinct functions in some tissues, and overlapping functions in others.
The DRSC/TRiP is engaged in a project in collaboration with the Perrimon and Bellen labs to generate resources useful for the study of paralogous genes in Drosophila.
In adherance with Harvard Medical School's response to the COVID-19 pandemic, the DRSC/TRiP-FGR and DRSC-BTRR will be closing our doors by 5 pm on Wed. March 16.
Services will be unavailable for at least 6-8 weeks but leaders and staff will be reachable by email, and related resources are available at the BDSC and DGRC in Indiana, and at Addgene, and information remains available at this site.
We are focused right now on minimizing the impact of the shut-down on our activities. In the future, we expect to be able to make use of the time to help our research...
Learn about DRSC/TRiP activities focused on using CRISPR activation to develop human disease models in a recently published Q&A with our Director, Dr. S.E. Mohr, who will be a speaker this spring at an upcoming genome editing conference in Boston, MA.
The DRSC congratulates Wilinski et al. at the University of Michigan for their release and publication of FlyScape, a tool for metabolic network visualization.
Rapid metabolic shifts occur during the transition between hunger and satiety in Drosophila melanogaster
Daniel Wilinski, Jasmine Winzeler, William Duren, Jenna L. Persons, Kristina J. Holme, Johan Mosquera, Morteza Khabiri, Jason M. Kinchen, Peter L. Freddolino, Alla Karnovsky & Monica Dus
The DRSC/TRiP will be represented at the GSA's The Allied Genetics Conference (TAGC) 2020, April 22 through 26, 2020, in Washington, D.C. For detailed information about the conference, please see the TAGC 2020 website. Read more about TAGC 2020 (Note: Event cancelled)
DRSC/TRiP Director Dr. Stephanie Mohr will be presenting a talk titled "Optimization of CRISPR technologies for development of Drosophila disease models" at the 4th Annual Genome Editing Congress, which is April 7 through 8, 2020, in Boston, MA.
DRSC/TRiP Director S. Mohr will be attending and presenting a poster on fly in vivo functional genomics technologies and bioinformatics resources at the 78th Annual Meeting of the Society for Developmental Biology.
