Users of TRiP RNAi and sgRNA fly stocks take note: the Weake lab at Purdue University brought to our attention that some TRiP fly stocks carry a mutant allele of seveneless. Jonathan Zirin worked with Spencer Escobedo and Vikki Weake, as well as with folks at the Bloomington Drosophila Stock Center, to quickly identify the source, sequence the mutant allele, and pubilsh a micropublication so we can get the details to the community. Bottom line, as stated in the micropublication, "The presence of the sev[21]  mutation will not generally affect the use of these stocks, as the X...

We have been taking a critical look at how we organize our online tools on the Online Tools Overview page. And more generally, we have been thinking about new ways to spread the word about the many resources in our suite of online tools. One way that we at the DRSC like to think about these tools is how they fit into the start-to-finish order of events in a screen or other experimental project. Various tools help define lists of genes to be studied, help identify reagents for the study,...

Laboratories at the Skirball Institute at New York University and the Boyce Thompson Institute at Cornell University reported results of two different cell-based Drosophila RNAi screens in papers published this week. The screens have in common that they looked at interactions between the host insect cells and a microbe -- the endosymbiont Wolbachia in one study and baculovirus in the other. For more, check out the newly published studies. For both these screens, the DRSC provided libraries for screens that were then performed at the host institution.

We have two new online tools available: iProteinDB and BioLitMine.

Both continue our series of resources aimed at integrating existing information in new ways to facilitate data mining and development of new hypotheses. In addition, iProteinDB includes a new dataset related to post-transcriptional modification (in this case,...

At the DRSC/TRiP-Functional Genomics Resources, we are interested to let the community know about new resources we have built. We are also interested more broadly to help connect community members to additional resources that could help their research studies, foster collaborations, and build community.

One way in which we reach out to the community is by attending national and local fly group meetings. In 2018, this included or will include attendance at the ADRC fly meeting in Philly (spring 2018), and past or upcoming presentations at Flies on the Beach (FL),...